Intravenous immunoglobulins in patients with COVID-19-associated moderate-to-severe acute respiratory distress syndrome (ICAR): multicentre, double-blind, placebo-controlled, phase 3 trial

BACKGROUND: Acute respiratory distress syndrome (ARDS) is a major complication of COVID-19 and is associated with high mortality and morbidity. We aimed to assess whether intravenous immunoglobulins (IVIG) could improve outcomes by reducing inflammation-mediated lung injury. METHODS: In this multice...

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Detalles Bibliográficos
Autores principales: Mazeraud, Aurélien, Jamme, Matthieu, Mancusi, Rossella Letizia, Latroche, Claire, Megarbane, Bruno, Siami, Shidasp, Zarka, Jonathan, Moneger, Guy, Santoli, Francesco, Argaud, Laurent, Chillet, Patrick, Muller, Gregoire, Bruel, Cedric, Asfar, Pierre, Beloncle, Francois, Reignier, Jean, Vinsonneau, Christophe, Schimpf, Caroline, Amour, Julien, Goulenok, Cyril, Lemaitre, Caroline, Rohaut, Benjamin, Mateu, Philippe, De Rudnicki, Stephane, Mourvillier, Bruno, Declercq, Pierre-Louis, Schwebel, Carole, Stoclin, Annabelle, Garnier, Marc, Madeux, Benjamin, Gaudry, Stéphane, Bailly, Karine, Lamer, Christian, Aegerter, Philippe, Rieu, Christine, Sylla, Khaoussou, Lucas, Bruno, Sharshar, Tarek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2022
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8585489/
https://www.ncbi.nlm.nih.gov/pubmed/34774185
http://dx.doi.org/10.1016/S2213-2600(21)00440-9

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