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Clinical Trials of the BTK Inhibitors Ibrutinib and Acalabrutinib in Human Diseases Beyond B Cell Malignancies

The BTK inhibitors ibrutinib and acalabrutinib are FDA-approved drugs for the treatment of B cell malignances. Both drugs have demonstrated clinical efficacy and safety profiles superior to chemoimmunotherapy regimens in patients with chronic lymphocytic leukemia. Mounting preclinical and clinical e...

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Detalles Bibliográficos
Autores principales:	Zhu, Sining, Jung, Jaeyong, Victor, Eton, Arceo, Johann, Gokhale, Samantha, Xie, Ping
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Oncology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8585514/ https://www.ncbi.nlm.nih.gov/pubmed/34778053 http://dx.doi.org/10.3389/fonc.2021.737943

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