Regulation of a progenitor gene program by SOX4 is essential for mammary tumor proliferation

In breast cancer the transcription factor SOX4 has been shown to be associated with poor survival, increased tumor size and metastasis formation. This has mostly been attributed to the ability of SOX4 to regulate Epithelial-to-Mesenchymal-Transition (EMT). However, SOX4 regulates target gene transcr...

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Detalles Bibliográficos
Autores principales: Roukens, M. Guy, Frederiks, Cynthia L., Seinstra, Danielle, Braccioli, Luca, Khalil, Antoine A., Pals, Cornelieke, De Neck, Simon, Bornes, Laura, Beerling, Evelyne, Mokry, Michal, de Bruin, Alain, Westendorp, Bart, van Rheenen, Jacco, Coffer, Paul J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8585668/
https://www.ncbi.nlm.nih.gov/pubmed/34584219
http://dx.doi.org/10.1038/s41388-021-02004-z

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