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Role of Runx2 in Calcific Aortic Valve Disease in Mouse Models

Background: Calcific aortic valve disease is common in the aging population and is characterized by the histological changes of the aortic valves including extracellular matrix remodeling, osteochondrogenic differentiation, and calcification. Combined, these changes lead to aortic sclerosis, aortic...

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Detalles Bibliográficos
Autores principales: Dharmarajan, Subramanian, Speer, Mei Y., Pierce, Kate, Lally, Jake, Leaf, Elizabeth M., Lin, Mu-En, Scatena, Marta, Giachelli, Cecilia M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8585763/
https://www.ncbi.nlm.nih.gov/pubmed/34778386
http://dx.doi.org/10.3389/fcvm.2021.687210