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Role of Runx2 in Calcific Aortic Valve Disease in Mouse Models
Background: Calcific aortic valve disease is common in the aging population and is characterized by the histological changes of the aortic valves including extracellular matrix remodeling, osteochondrogenic differentiation, and calcification. Combined, these changes lead to aortic sclerosis, aortic...
Autores principales: | Dharmarajan, Subramanian, Speer, Mei Y., Pierce, Kate, Lally, Jake, Leaf, Elizabeth M., Lin, Mu-En, Scatena, Marta, Giachelli, Cecilia M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8585763/ https://www.ncbi.nlm.nih.gov/pubmed/34778386 http://dx.doi.org/10.3389/fcvm.2021.687210 |
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