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Limitations of Antibiotic MIC-Based PK-PD Metrics: Looking Back to Move Forward
Within a few years after the first successful clinical use of penicillin, investigations were conducted in animal infection models to explore a range of factors that were considered likely to influence the antibacterial response to the drug. Those studies identified that the response was influenced...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Frontiers Media S.A.
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8585766/ https://www.ncbi.nlm.nih.gov/pubmed/34776982 http://dx.doi.org/10.3389/fphar.2021.770518 |