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Cohort and Trajectory Analysis in Multi-Agent Support Systems for Cancer Survivors

In the past decades, the incidence rate of cancer has steadily risen. Although advances in early and accurate detection have increased cancer survival chances, these patients must cope with physical and psychological sequelae. The lack of personalized support and assistance after discharge may lead...

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Autores principales: Manzo, Gaetano, Calvaresi, Davide, Jimenez-del-Toro, Oscar, Calbimonte, Jean-Paul, Schumacher, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8585846/
https://www.ncbi.nlm.nih.gov/pubmed/34766229
http://dx.doi.org/10.1007/s10916-021-01770-3
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author Manzo, Gaetano
Calvaresi, Davide
Jimenez-del-Toro, Oscar
Calbimonte, Jean-Paul
Schumacher, Michael
author_facet Manzo, Gaetano
Calvaresi, Davide
Jimenez-del-Toro, Oscar
Calbimonte, Jean-Paul
Schumacher, Michael
author_sort Manzo, Gaetano
collection PubMed
description In the past decades, the incidence rate of cancer has steadily risen. Although advances in early and accurate detection have increased cancer survival chances, these patients must cope with physical and psychological sequelae. The lack of personalized support and assistance after discharge may lead to a rapid diminution of their physical abilities, cognitive impairment, and reduced quality of life. This paper proposes a personalized support system for cancer survivors based on a cohort and trajectory analysis (CTA) module integrated within an agent-based personalized chatbot named EREBOTS. The CTA module relies on survival estimation models, machine learning, and deep learning techniques. It provides clinicians with supporting evidence for choosing a personalized treatment, while allowing patients to benefit from tailored suggestions adapted to their conditions and trajectories. The development of the CTA within the EREBOTS framework enables to effectively evaluate the significance of prognostic variables, detect patient’s high-risk markers, and support treatment decisions.
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spelling pubmed-85858462021-11-15 Cohort and Trajectory Analysis in Multi-Agent Support Systems for Cancer Survivors Manzo, Gaetano Calvaresi, Davide Jimenez-del-Toro, Oscar Calbimonte, Jean-Paul Schumacher, Michael J Med Syst Patient Facing Systems In the past decades, the incidence rate of cancer has steadily risen. Although advances in early and accurate detection have increased cancer survival chances, these patients must cope with physical and psychological sequelae. The lack of personalized support and assistance after discharge may lead to a rapid diminution of their physical abilities, cognitive impairment, and reduced quality of life. This paper proposes a personalized support system for cancer survivors based on a cohort and trajectory analysis (CTA) module integrated within an agent-based personalized chatbot named EREBOTS. The CTA module relies on survival estimation models, machine learning, and deep learning techniques. It provides clinicians with supporting evidence for choosing a personalized treatment, while allowing patients to benefit from tailored suggestions adapted to their conditions and trajectories. The development of the CTA within the EREBOTS framework enables to effectively evaluate the significance of prognostic variables, detect patient’s high-risk markers, and support treatment decisions. Springer US 2021-11-11 2021 /pmc/articles/PMC8585846/ /pubmed/34766229 http://dx.doi.org/10.1007/s10916-021-01770-3 Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Patient Facing Systems
Manzo, Gaetano
Calvaresi, Davide
Jimenez-del-Toro, Oscar
Calbimonte, Jean-Paul
Schumacher, Michael
Cohort and Trajectory Analysis in Multi-Agent Support Systems for Cancer Survivors
title Cohort and Trajectory Analysis in Multi-Agent Support Systems for Cancer Survivors
title_full Cohort and Trajectory Analysis in Multi-Agent Support Systems for Cancer Survivors
title_fullStr Cohort and Trajectory Analysis in Multi-Agent Support Systems for Cancer Survivors
title_full_unstemmed Cohort and Trajectory Analysis in Multi-Agent Support Systems for Cancer Survivors
title_short Cohort and Trajectory Analysis in Multi-Agent Support Systems for Cancer Survivors
title_sort cohort and trajectory analysis in multi-agent support systems for cancer survivors
topic Patient Facing Systems
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8585846/
https://www.ncbi.nlm.nih.gov/pubmed/34766229
http://dx.doi.org/10.1007/s10916-021-01770-3
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