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A Perspective on Chronic and Long-Lasting Anorexia Nervosa

Anorexia Nervosa (AN) is a severe eating disorder which typically develops in younger females. Many studies focus on this specific population, a majority of which will eventually partially or fully recover. A minority will become chronic despite extensive treatment. These patients are treatment-resi...

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Autores principales: Speciani, Maurizio, Barak, Yoram, Damanhuri, Hanafi, De Ronchi, Diana, Panariello, Fabio, Atti, Anna Rita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8585925/
https://www.ncbi.nlm.nih.gov/pubmed/34777061
http://dx.doi.org/10.3389/fpsyt.2021.756669
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author Speciani, Maurizio
Barak, Yoram
Damanhuri, Hanafi
De Ronchi, Diana
Panariello, Fabio
Atti, Anna Rita
author_facet Speciani, Maurizio
Barak, Yoram
Damanhuri, Hanafi
De Ronchi, Diana
Panariello, Fabio
Atti, Anna Rita
author_sort Speciani, Maurizio
collection PubMed
description Anorexia Nervosa (AN) is a severe eating disorder which typically develops in younger females. Many studies focus on this specific population, a majority of which will eventually partially or fully recover. A minority will become chronic despite extensive treatment. These patients are treatment-resistant and may not necessarily benefit from usual treatment. In this article we will reflect on possible mechanisms which may explain the maintenance of disease, and especially on the possible role of affective and anxiety disturbances. We will use, due to the lack of large-scale studies, data from risk and prognostic factors, treatment options and neurobiological correlates in chronic AN patients. Lastly, we will propose how these elements may advise further research and treatments.
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spelling pubmed-85859252021-11-13 A Perspective on Chronic and Long-Lasting Anorexia Nervosa Speciani, Maurizio Barak, Yoram Damanhuri, Hanafi De Ronchi, Diana Panariello, Fabio Atti, Anna Rita Front Psychiatry Psychiatry Anorexia Nervosa (AN) is a severe eating disorder which typically develops in younger females. Many studies focus on this specific population, a majority of which will eventually partially or fully recover. A minority will become chronic despite extensive treatment. These patients are treatment-resistant and may not necessarily benefit from usual treatment. In this article we will reflect on possible mechanisms which may explain the maintenance of disease, and especially on the possible role of affective and anxiety disturbances. We will use, due to the lack of large-scale studies, data from risk and prognostic factors, treatment options and neurobiological correlates in chronic AN patients. Lastly, we will propose how these elements may advise further research and treatments. Frontiers Media S.A. 2021-10-29 /pmc/articles/PMC8585925/ /pubmed/34777061 http://dx.doi.org/10.3389/fpsyt.2021.756669 Text en Copyright © 2021 Speciani, Barak, Damanhuri, De Ronchi, Panariello and Atti. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Psychiatry
Speciani, Maurizio
Barak, Yoram
Damanhuri, Hanafi
De Ronchi, Diana
Panariello, Fabio
Atti, Anna Rita
A Perspective on Chronic and Long-Lasting Anorexia Nervosa
title A Perspective on Chronic and Long-Lasting Anorexia Nervosa
title_full A Perspective on Chronic and Long-Lasting Anorexia Nervosa
title_fullStr A Perspective on Chronic and Long-Lasting Anorexia Nervosa
title_full_unstemmed A Perspective on Chronic and Long-Lasting Anorexia Nervosa
title_short A Perspective on Chronic and Long-Lasting Anorexia Nervosa
title_sort perspective on chronic and long-lasting anorexia nervosa
topic Psychiatry
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8585925/
https://www.ncbi.nlm.nih.gov/pubmed/34777061
http://dx.doi.org/10.3389/fpsyt.2021.756669
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