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Antibody-guided design and identification of CD25-binding small antibody mimetics using mammalian cell surface display
Small antibody mimetics that contain high-affinity target-binding peptides can be lower cost alternatives to monoclonal antibodies (mAbs). We have recently developed a method to create small antibody mimetics called FLuctuation-regulated Affinity Proteins (FLAPs), which consist of a small protein sc...
Autores principales: | See, Kyra, Kadonosono, Tetsuya, Miyamoto, Kotaro, Tsubaki, Takuya, Ota, Yumi, Katsumi, Marina, Ryo, Sumoe, Aida, Kazuki, Minegishi, Misa, Isozaki, Tatsuhiro, Kuchimaru, Takahiro, Kizaka-Kondoh, Shinae |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8585965/ https://www.ncbi.nlm.nih.gov/pubmed/34764369 http://dx.doi.org/10.1038/s41598-021-01603-w |
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