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Targeting CD38 in acute myeloid leukemia interferes with leukemia trafficking and induces phagocytosis

Targeting the interaction between leukemic cells and the microenvironment is an appealing approach to enhance the therapeutic efficacy in acute myeloid leukemia (AML). AML infiltration induces a significant release of inflammatory cytokines in the human bone marrow niche which accelerates leukemogen...

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Detalles Bibliográficos
Autores principales: Farber, Meike, Chen, Yiyang, Arnold, Lucas, Möllmann, Michael, Boog-Whiteside, Eva, Lin, Yu-An, Reinhardt, H. Christian, Dührsen, Ulrich, Hanoun, Maher
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8586007/
https://www.ncbi.nlm.nih.gov/pubmed/34764342
http://dx.doi.org/10.1038/s41598-021-01300-8