Cargando…

Targeting CD38 in acute myeloid leukemia interferes with leukemia trafficking and induces phagocytosis

Targeting the interaction between leukemic cells and the microenvironment is an appealing approach to enhance the therapeutic efficacy in acute myeloid leukemia (AML). AML infiltration induces a significant release of inflammatory cytokines in the human bone marrow niche which accelerates leukemogen...

Descripción completa

Detalles Bibliográficos
Autores principales:	Farber, Meike, Chen, Yiyang, Arnold, Lucas, Möllmann, Michael, Boog-Whiteside, Eva, Lin, Yu-An, Reinhardt, H. Christian, Dührsen, Ulrich, Hanoun, Maher
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8586007/ https://www.ncbi.nlm.nih.gov/pubmed/34764342 http://dx.doi.org/10.1038/s41598-021-01300-8

Ejemplares similares

Circulating exosomes carrying an immunosuppressive cargo interfere with cellular immunotherapy in acute myeloid leukemia
por: Hong, Chang-Sook, et al.
Publicado: (2017)

Epigenetic Silencing of the Circadian Clock Gene CRY1 is Associated with an Indolent Clinical Course in Chronic Lymphocytic Leukemia
por: Hanoun, Maher, et al.
Publicado: (2012)

Taking the STING out of acute myeloid leukemia through macrophage-mediated phagocytosis
por: Dalton, William Brian, et al.
Publicado: (2022)

CpG stimulation of chronic lymphocytic leukemia cells induces a polarized cell shape and promotes migration in vitro and in vivo
por: Dampmann, Maria, et al.
Publicado: (2020)

Redirecting the Immune Microenvironment in Acute Myeloid Leukemia
por: Sendker, Stephanie, et al.
Publicado: (2021)

Vesicular trafficking is a key determinant of the statin response in acute myeloid leukemia
por: Krosl, Jana, et al.
Publicado: (2022)

Anti-leukemic effect of CDK9 inhibition in T-cell prolymphocytic leukemia
por: Johansson, Patricia, et al.
Publicado: (2020)

Circulating exosomes carrying an immunosuppressive cargo may interfere with adoptive cell therapies in leukemia
por: Boyiadzis, Michael, et al.
Publicado: (2015)

Functional characterization of the ectopically expressed olfactory receptor 2AT4 in human myelogenous leukemia
por: Manteniotis, S, et al.
Publicado: (2016)

Pediatric Acute Myeloid Leukemia—Past, Present, and Future
por: Reinhardt, Dirk, et al.
Publicado: (2022)

SIRPα-antibody fusion proteins stimulate phagocytosis and promote elimination of acute myeloid leukemia cells
por: Ponce, Laia Pascual, et al.
Publicado: (2017)

CYLD stimulates macrophage phagocytosis of leukemic cells through STAT1 signalling in acute myeloid leukemia
por: Huyen, Nguyen Thanh, et al.
Publicado: (2023)

RAB27B controls palmitoylation-dependent NRAS trafficking and signaling in myeloid leukemia
por: Ren, Jian-Gang, et al.
Publicado: (2023)

Plasma Exosomes as Markers of Therapeutic Response in Patients with Acute Myeloid Leukemia
por: Hong, Chang-Sook, et al.
Publicado: (2014)

Treatment of Relapsed Acute Myeloid Leukemia
por: Thol, Felicitas, et al.
Publicado: (2020)

Isolation and Characterization of CD34+ Blast-Derived Exosomes in Acute Myeloid Leukemia
por: Hong, Chang Sook, et al.
Publicado: (2014)

High frequency of CD34+CD38-/low immature leukemia cells is correlated with unfavorable prognosis in acute myeloid leukemia
por: Plesa, Adriana, et al.
Publicado: (2017)

Chronic myeloid leukemia versus acute myeloid leukemia in patients with retinoblastoma
por: Leahey, Ann-Marie, et al.
Publicado: (2021)

Characteristics and outcome of patients with acute myeloid leukemia and trisomy 4
por: Kayser, Sabine, et al.
Publicado: (2022)

LC3-associated phagocytosis in bone marrow macrophages suppresses acute myeloid leukemia progression through STING activation
por: Moore, Jamie A., et al.
Publicado: (2022)

Meningioma 1 is indispensable for mixed lineage leukemia-rearranged acute myeloid leukemia
por: Sharma, Amit, et al.
Publicado: (2020)

Progranulin Is a Novel Independent Predictor of Disease Progression and Overall Survival in Chronic Lymphocytic Leukemia
por: Göbel, Maria, et al.
Publicado: (2013)

Acute Myeloid Leukemia
Publicado: (2019)

Acute myeloid leukemia
por: Haferlach, Torsten
Publicado: (2019)

Chronic myeloid leukemia
por: Hantschel, Oliver
Publicado: (2019)

Acute myeloid leukemia
por: Ossenkoppele, Gert
Publicado: (2018)

Chronic myeloid leukemia
por: Sauβele, Susanne
Publicado: (2018)

Targeting CD38 for acute leukemia
por: Zhong, Xushu, et al.
Publicado: (2022)

Leukemia stem cells: the root of chronic myeloid leukemia
por: Zhou, Hong, et al.
Publicado: (2015)

Coexistence of Chronic Lymphocytic Leukemia and Acute Myeloid Leukemia
por: Milosevic, Ivana
Publicado: (2016)

Transformation of Chronic Myeloid Leukemia to Acute Biphenotypic Leukemia
por: Ivanov, Stanislav, et al.
Publicado: (2020)

Potent anti-leukemic activity of a specific cyclin-dependent kinase 9 inhibitor in mouse models of chronic lymphocytic leukemia
por: Göthert, Joachim R., et al.
Publicado: (2018)

89723 CD105-targeted CAR T cells for the treatment of acute myeloid leukemia
por: Lontos, Konstantinos, et al.
Publicado: (2021)

Mutated IKZF1 is an independent marker of adverse risk in acute myeloid leukemia
por: Eckardt, Jan-Niklas, et al.
Publicado: (2023)

Acute myeloid leukemia in a 38-year-old hemodialyzed patient with von Hippel-Lindau disease
por: Labno-Kirszniok, Katarzyna, et al.
Publicado: (2013)

Molecular profiling and clinical implications of patients with acute myeloid leukemia and extramedullary manifestations
por: Eckardt, Jan-Niklas, et al.
Publicado: (2022)

Immunotherapy for acute leukemia
por: Boyiadzis, Michael, et al.
Publicado: (2015)

Isolated leukemia cutis as extramedullary relapse of acute myeloid leukemia
por: Dadrass, Farinoosh, et al.
Publicado: (2022)

Chronic myeloid leukemia developing in treated acute promyelocytic leukemia
por: Abbasi, Abdul Muqtadir, et al.
Publicado: (2022)

Therapeutic targeting of leukemia stem cells in acute myeloid leukemia
por: Barbosa, Karina, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_c9qdfms5slpfma99qvdrkn825c