A tissue-bioengineering strategy for modeling rare human kidney diseases in vivo

The lack of animal models for some human diseases precludes our understanding of disease mechanisms and our ability to test prospective therapies in vivo. Generation of kidney organoids from Tuberous Sclerosis Complex (TSC) patient-derived-hiPSCs allows us to recapitulate a rare kidney tumor called...

Descripción completa

Detalles Bibliográficos
Autores principales: Hernandez, J. O. R., Wang, X., Vazquez-Segoviano, M., Lopez-Marfil, M., Sobral-Reyes, M. F., Moran-Horowich, A., Sundberg, M., Lopez-Cantu, D. O., Probst, C. K., Ruiz-Esparza, G. U., Giannikou, K., Abdi, R., Henske, E. P., Kwiatkowski, D. J., Sahin, M., Lemos, D. R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8586030/
https://www.ncbi.nlm.nih.gov/pubmed/34764250
http://dx.doi.org/10.1038/s41467-021-26596-y

Ejemplares similares

Ejemplares similares