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Angiopoietin-1 protects against endotoxin-induced neonatal lung injury and alveolar simplification in mice.

BACKGROUND: Sepsis in premature newborns is a risk factor for bronchopulmonary dysplasia (BPD), but underlying mechanisms of lung injury remain unclear. Aberrant expression of endothelial cell (EC) angiopoietin 2 (ANGPT2) disrupts angiopoietin 1 (ANGPT1)/TIE2-mediated endothelial quiescence, and is...

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Detalles Bibliográficos
Autores principales:	Salimi, Umar, Menden, Heather L., Mabry, Sherry M., Xia, Sheng, Sampath, Venkatesh
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8586034/ https://www.ncbi.nlm.nih.gov/pubmed/33980990 http://dx.doi.org/10.1038/s41390-021-01544-0

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