Oliceridine Exhibits Improved Tolerability Compared to Morphine at Equianalgesic Conditions: Exploratory Analysis from Two Phase 3 Randomized Placebo and Active Controlled Trials

INTRODUCTION: In the management of postoperative acute moderate-to-severe pain, opioids remain an important component. However, conventional opioids have a narrow therapeutic index and are associated with dose-limiting opioid-related adverse events (ORAEs) that can result in worse patient outcomes....

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Detalles Bibliográficos
Autores principales: Hammer, Gregory B., Khanna, Ashish K., Michalsky, Cathy, Wase, Linda, Demitrack, Mark A., Little, Roderick, Fossler, Michael J., Ayad, Sabry
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Healthcare 2021
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8586048/
https://www.ncbi.nlm.nih.gov/pubmed/34351590
http://dx.doi.org/10.1007/s40122-021-00299-0

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