A Review of Platelet-Activating Factor As a Potential Contributor to Morbidity and Mortality Associated with Severe COVID-19

The precise mechanisms of pathology in severe COVID-19 remains elusive. Current evidence suggests that inflammatory mediators are responsible for the manifestation of clinical symptoms that precedes a fatal response to infection. This review examines the nature of platelet activating factor and emph...

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Detalles Bibliográficos
Autores principales: Klein, Mark, Dao, Vinh, Khan, Fatima
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8586171/
https://www.ncbi.nlm.nih.gov/pubmed/34755565
http://dx.doi.org/10.1177/10760296211051764
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author Klein, Mark
Dao, Vinh
Khan, Fatima
author_facet Klein, Mark
Dao, Vinh
Khan, Fatima
author_sort Klein, Mark
collection PubMed
description The precise mechanisms of pathology in severe COVID-19 remains elusive. Current evidence suggests that inflammatory mediators are responsible for the manifestation of clinical symptoms that precedes a fatal response to infection. This review examines the nature of platelet activating factor and emphasizes the similarities between the physiological effects of platelet activating factor and the clinical complications of severe COVID-19.
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spelling pubmed-85861712021-11-13 A Review of Platelet-Activating Factor As a Potential Contributor to Morbidity and Mortality Associated with Severe COVID-19 Klein, Mark Dao, Vinh Khan, Fatima Clin Appl Thromb Hemost Review The precise mechanisms of pathology in severe COVID-19 remains elusive. Current evidence suggests that inflammatory mediators are responsible for the manifestation of clinical symptoms that precedes a fatal response to infection. This review examines the nature of platelet activating factor and emphasizes the similarities between the physiological effects of platelet activating factor and the clinical complications of severe COVID-19. SAGE Publications 2021-11-10 /pmc/articles/PMC8586171/ /pubmed/34755565 http://dx.doi.org/10.1177/10760296211051764 Text en © The Author(s) 2021 https://creativecommons.org/licenses/by-nc/4.0/This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access page (https://us.sagepub.com/en-us/nam/open-access-at-sage).
spellingShingle Review
Klein, Mark
Dao, Vinh
Khan, Fatima
A Review of Platelet-Activating Factor As a Potential Contributor to Morbidity and Mortality Associated with Severe COVID-19
title A Review of Platelet-Activating Factor As a Potential Contributor to Morbidity and Mortality Associated with Severe COVID-19
title_full A Review of Platelet-Activating Factor As a Potential Contributor to Morbidity and Mortality Associated with Severe COVID-19
title_fullStr A Review of Platelet-Activating Factor As a Potential Contributor to Morbidity and Mortality Associated with Severe COVID-19
title_full_unstemmed A Review of Platelet-Activating Factor As a Potential Contributor to Morbidity and Mortality Associated with Severe COVID-19
title_short A Review of Platelet-Activating Factor As a Potential Contributor to Morbidity and Mortality Associated with Severe COVID-19
title_sort review of platelet-activating factor as a potential contributor to morbidity and mortality associated with severe covid-19
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8586171/
https://www.ncbi.nlm.nih.gov/pubmed/34755565
http://dx.doi.org/10.1177/10760296211051764
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