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Mesenchymal stromal cell apoptosis is required for their therapeutic function

Multipotent mesenchymal stromal cells (MSCs) ameliorate a wide range of diseases in preclinical models, but the lack of clarity around their mechanisms of action has impeded their clinical utility. The therapeutic effects of MSCs are often attributed to bioactive molecules secreted by viable MSCs. H...

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Detalles Bibliográficos
Autores principales:	Pang, Swee Heng Milon, D’Rozario, Joshua, Mendonca, Senora, Bhuvan, Tejasvini, Payne, Natalie L., Zheng, Di, Hisana, Assifa, Wallis, Georgia, Barugahare, Adele, Powell, David, Rautela, Jai, Huntington, Nicholas D., Dewson, Grant, Huang, David C. S., Gray, Daniel H. D., Heng, Tracy S. P.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8586224/ https://www.ncbi.nlm.nih.gov/pubmed/34764248 http://dx.doi.org/10.1038/s41467-021-26834-3

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