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Engineered extracellular vesicles for concurrent Anti-PDL1 immunotherapy and chemotherapy

Immune checkpoint inhibitors (ICI) targeting PD-1/PD-L1 have been approved for the treatment of a variety of cancers. However, the efficacy of antibody-based ICIs could be further improved by mitigating anti-drug antibodies, proteolytic cleavage, and on-target off-tumor toxicity. One strategy for ac...

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Detalles Bibliográficos
Autores principales:	Chen, Yundi, Wang, Lixue, Zheng, Mingfeng, Zhu, Chuandong, Wang, Guosheng, Xia, Yiqiu, Blumenthal, Ethan J., Mao, Wenjun, Wan, Yuan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	KeAi Publishing 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8586263/ https://www.ncbi.nlm.nih.gov/pubmed/34820569 http://dx.doi.org/10.1016/j.bioactmat.2021.07.012

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