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Spontaneous pulmonary emphysema in mice lacking all three nitric oxide synthase isoforms
The roles of endogenous nitric oxide (NO) derived from the entire NO synthases (NOSs) system have yet to be fully elucidated. We addressed this issue in mice in which all three NOS isoforms were deleted. Under basal conditions, the triple n/i/eNOSs(−/−) mice displayed significantly longer mean alveo...
Autores principales: | Kato, Kaori, Tsutsui, Masato, Noguchi, Shingo, Iha, Yukitoshi, Naito, Keisuke, Ogoshi, Takaaki, Nishida, Chinatsu, Tahara, Masahiro, Yamashita, Hirotaka, Wang, Ke-Yong, Toyohira, Yumiko, Yanagihara, Nobuyuki, Masuzaki, Hiroaki, Shimokawa, Hiroaki, Tanimoto, Akihide, Yatera, Kazuhiro |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8586362/ https://www.ncbi.nlm.nih.gov/pubmed/34764368 http://dx.doi.org/10.1038/s41598-021-01453-6 |
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