Cargando…

Extracellular Vesicles in Serum and Central Nervous System Tissues Contain microRNA Signatures in Sporadic Amyotrophic Lateral Sclerosis

Amyotrophic lateral sclerosis (ALS) is a terminalneurodegenerative disease. Clinical and molecular observations suggest that ALS pathology originates at a single site and spreads in an organized and prion-like manner, possibly driven by extracellular vesicles. Extracellular vesicles (EVs) transfer c...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lo, Ting-wen, Figueroa-Romero, Claudia, Hur, Junguk, Pacut, Crystal, Stoll, Evan, Spring, Calvin, Lewis, Rose, Nair, Athul, Goutman, Stephen A., Sakowski, Stacey A., Nagrath, Sunitha, Feldman, Eva L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8586523/ https://www.ncbi.nlm.nih.gov/pubmed/34776863 http://dx.doi.org/10.3389/fnmol.2021.739016

Ejemplares similares

Metabolomics identifies shared lipid pathways in independent amyotrophic lateral sclerosis cohorts
por: Goutman, Stephen A, et al.
Publicado: (2022)

Identification of Epigenetically Altered Genes in Sporadic Amyotrophic Lateral Sclerosis
por: Figueroa-Romero, Claudia, et al.
Publicado: (2012)

Tofacitinib Suppresses Natural Killer Cells In Vitro and In Vivo: Implications for Amyotrophic Lateral Sclerosis
por: Figueroa-Romero, Claudia, et al.
Publicado: (2022)

Genome-wide DNA methylation profiling of human diabetic peripheral neuropathy in subjects with type 2 diabetes mellitus
por: Guo, Kai, et al.
Publicado: (2019)

Intraspinal Neural Stem Cell Transplantation in Amyotrophic Lateral Sclerosis: Phase 1 Trial Outcomes
por: Feldman, Eva L, et al.
Publicado: (2014)

Genome-wide profiling of DNA methylation and gene expression identifies candidate genes for human diabetic neuropathy
por: Guo, Kai, et al.
Publicado: (2020)

Correction to: Genome-wide profiling of DNA methylation and gene expression identifies candidate genes for human diabetic neuropathy
por: Guo, Kai, et al.
Publicado: (2020)

Cytoplasmic TDP43 Binds microRNAs: New Disease Targets in Amyotrophic Lateral Sclerosis
por: Paez-Colasante, Ximena, et al.
Publicado: (2020)

Gut microbiota in a mouse model of obesity and peripheral neuropathy associated with plasma and nerve lipidomics and nerve transcriptomics
por: Guo, Kai, et al.
Publicado: (2023)

Pathological Proteins Are Transported by Extracellular Vesicles of Sporadic Amyotrophic Lateral Sclerosis Patients
por: Sproviero, Daisy, et al.
Publicado: (2018)

Muscle cells of sporadic amyotrophic lateral sclerosis patients secrete neurotoxic vesicles
por: Le Gall, Laura, et al.
Publicado: (2022)

Abnormal RNA stability in amyotrophic lateral sclerosis
por: Tank, E. M., et al.
Publicado: (2018)

Increased ratio of circulating neutrophils to monocytes in amyotrophic lateral sclerosis
por: Murdock, Benjamin J., et al.
Publicado: (2016)

Early life metal dysregulation in amyotrophic lateral sclerosis
por: Figueroa‐Romero, Claudia, et al.
Publicado: (2020)

Amyotrophic Lateral Sclerosis Survival Associates With Neutrophils in a Sex-specific Manner
por: Murdock, Benjamin J., et al.
Publicado: (2021)

Dysregulated biodynamics in metabolic attractor systems precede the emergence of amyotrophic lateral sclerosis
por: Curtin, Paul, et al.
Publicado: (2020)

Human Cortical Neural Stem Cells Expressing Insulin-Like Growth Factor-I: A Novel Cellular Therapy for Alzheimer’s Disease
por: McGinley, Lisa M., et al.
Publicado: (2016)

The Role of Oxidative Stress in Nervous System Aging
por: Sims-Robinson, Catrina, et al.
Publicado: (2013)

Gene Therapy in Amyotrophic Lateral Sclerosis
por: Fang, Ton, et al.
Publicado: (2022)

Targeted Drug Delivery to the Central Nervous System Using Extracellular Vesicles
por: Zhou, Lina, et al.
Publicado: (2022)

Genetic variability in sporadic amyotrophic lateral sclerosis
por: Van Daele, Sien Hilde, et al.
Publicado: (2023)

Untargeted metabolomics yields insight into ALS disease mechanisms
por: Goutman, Stephen A, et al.
Publicado: (2020)

Palmitate and glucose increase amyloid precursor protein in extracellular vesicles: Missing link between metabolic syndrome and Alzheimer's disease
por: Kim, Bhumsoo, et al.
Publicado: (2023)

The risk to relatives of patients with sporadic amyotrophic lateral sclerosis
por: Hanby, Martha F., et al.
Publicado: (2011)

Neutrophil-to-lymphocyte ratio in sporadic amyotrophic lateral sclerosis
por: Wei, Qian-Qian, et al.
Publicado: (2021)

Environmental Risk Factors and Amyotrophic Lateral Sclerosis (ALS): A Case-Control Study of ALS in Michigan
por: Yu, Yu, et al.
Publicado: (2014)

Targeted Exon Capture and Sequencing in Sporadic Amyotrophic Lateral Sclerosis
por: Couthouis, Julien, et al.
Publicado: (2014)

Cognitive Impairment in Chinese Patients with Sporadic Amyotrophic Lateral Sclerosis
por: Cui, Bo, et al.
Publicado: (2015)

Chitotriosidase - a putative biomarker for sporadic amyotrophic lateral sclerosis
por: Varghese, Anu Mary, et al.
Publicado: (2013)

Misfolded SOD1 pathology in sporadic Amyotrophic Lateral Sclerosis
por: Paré, Bastien, et al.
Publicado: (2018)

Novel Genetic Signatures Associated With Sporadic Amyotrophic Lateral Sclerosis
por: Logan, Robert, et al.
Publicado: (2022)

Diagnostic Circulating miRNAs in Sporadic Amyotrophic Lateral Sclerosis
por: Panio, A., et al.
Publicado: (2022)

Spectrum and frequency of genetic variants in sporadic amyotrophic lateral sclerosis
por: Ruf, Wolfgang P, et al.
Publicado: (2023)

Three nervous system-specific expressed genes are potential biomarkers for the diagnosis of sporadic amyotrophic lateral sclerosis through a bioinformatic analysis
por: Liao, Yifu, et al.
Publicado: (2023)

TDP-43 Is Not a Common Cause of Sporadic Amyotrophic Lateral Sclerosis
por: Guerreiro, Rita J., et al.
Publicado: (2008)

Restless Legs Syndrome in Chinese Patients With Sporadic Amyotrophic Lateral Sclerosis
por: Liu, Shuangwu, et al.
Publicado: (2018)

Fungal-contaminated grass and well water and sporadic amyotrophic lateral sclerosis
por: French, Peter William, et al.
Publicado: (2019)

Neuronal mitochondrial dysfunction in sporadic amyotrophic lateral sclerosis is developmentally regulated
por: Singh, Tanisha, et al.
Publicado: (2021)

Randomized phase 2 study of perampanel for sporadic amyotrophic lateral sclerosis
por: Aizawa, Hitoshi, et al.
Publicado: (2021)

Genetic Analysis of Tryptophan Metabolism Genes in Sporadic Amyotrophic Lateral Sclerosis
por: Fifita, Jennifer A., et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_ftog0444b1nhk0mkq05fq4cfar