Lomustine and nimustine exert efficient antitumor effects against glioblastoma models with acquired temozolomide resistance

Glioblastomas (GBM) often acquire resistance against temozolomide (TMZ) after continuous treatment and recur as TMZ‐resistant GBM (TMZ‐R‐GBM). Lomustine (CCNU) and nimustine (ACNU), which were previously used as standard therapeutic agents against GBM before TMZ, have occasionally been used for the...

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Detalles Bibliográficos
Autores principales: Yamamuro, Shun, Takahashi, Masamichi, Satomi, Kaishi, Sasaki, Nobuyoshi, Kobayashi, Tatsuya, Uchida, Eita, Kawauchi, Daisuke, Nakano, Tomoyuki, Fujii, Takashi, Narita, Yoshitaka, Kondo, Akihide, Wada, Kojiro, Yoshino, Atsuo, Ichimura, Koichi, Tomiyama, Arata
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8586660/
https://www.ncbi.nlm.nih.gov/pubmed/34536314
http://dx.doi.org/10.1111/cas.15141

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