WEE1 inhibitor and ataxia telangiectasia and RAD3‐related inhibitor trigger stimulator of interferon gene‐dependent immune response and enhance tumor treatment efficacy through programmed death‐ligand 1 blockade

WEE1 plays an important role in the regulation of cell cycle G2/M checkpoints and DNA damage response (DDR). Inhibition of WEE1 can increase the instability of the genome and have anti–tumor effects in some solid tumors. However, it has certain limitations for multiple cancer cells from different li...

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Detalles Bibliográficos
Autores principales: Wu, Xue, Kang, Xiaoyan, Zhang, Xiaoxiao, Xie, Wan, Su, Yue, Liu, Xiaoyu, Guo, Lili, Guo, Ensong, Li, Fuxia, Hu, Dianxing, Qin, Xu, Fu, Yu, Peng, Wenju, Jia, Jiedong, Wang, Changyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8586668/
https://www.ncbi.nlm.nih.gov/pubmed/34382294
http://dx.doi.org/10.1111/cas.15108

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