Measuring Vaccine Efficacy Against Infection and Disease in Clinical Trials: Sources and Magnitude of Bias in Coronavirus Disease 2019 (COVID-19) Vaccine Efficacy Estimates

BACKGROUND: Phase III trials have estimated coronavirus disease 2019 (COVID-19) vaccine efficacy (VE) against symptomatic and asymptomatic infection. We explore the direction and magnitude of potential biases in these estimates and their implications for vaccine protection against infection and agai...

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Detalles Bibliográficos
Autores principales: Williams, Lucy R, Ferguson, Neil M, Donnelly, Christl A, Grassly, Nicholas C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Major Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8586723/
https://www.ncbi.nlm.nih.gov/pubmed/34698827
http://dx.doi.org/10.1093/cid/ciab914

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8586723/
https://www.ncbi.nlm.nih.gov/pubmed/34698827
http://dx.doi.org/10.1093/cid/ciab914

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