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Measuring Vaccine Efficacy Against Infection and Disease in Clinical Trials: Sources and Magnitude of Bias in Coronavirus Disease 2019 (COVID-19) Vaccine Efficacy Estimates

BACKGROUND: Phase III trials have estimated coronavirus disease 2019 (COVID-19) vaccine efficacy (VE) against symptomatic and asymptomatic infection. We explore the direction and magnitude of potential biases in these estimates and their implications for vaccine protection against infection and agai...

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Detalles Bibliográficos
Autores principales:	Williams, Lucy R, Ferguson, Neil M, Donnelly, Christl A, Grassly, Nicholas C
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2021
Materias:	Major Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8586723/ https://www.ncbi.nlm.nih.gov/pubmed/34698827 http://dx.doi.org/10.1093/cid/ciab914

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