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Dibenzofuran Derivatives Inspired from Cercosporamide as Dual Inhibitors of Pim and CLK1 Kinases

Pim kinases (proviral integration site for Moloney murine leukemia virus kinases) are overexpressed in various types of hematological malignancies and solid carcinomas, and promote cell proliferation and survival. Thus, Pim kinases are validated as targets for antitumor therapy. In this context, our...

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Detalles Bibliográficos
Autores principales: Dao, Viet Hung, Ourliac-Garnier, Isabelle, Logé, Cédric, McCarthy, Florence O., Bach, Stéphane, da Silva, Teresinha Gonçalves, Denevault-Sabourin, Caroline, Thiéfaine, Jérôme, Baratte, Blandine, Robert, Thomas, Gouilleux, Fabrice, Brachet-Botineau, Marie, Bazin, Marc-Antoine, Marchand, Pascal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8587151/
https://www.ncbi.nlm.nih.gov/pubmed/34770981
http://dx.doi.org/10.3390/molecules26216572