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Unveiling the Effect of Low pH on the SARS-CoV-2 Main Protease by Molecular Dynamics Simulations

(1) Background: Main Protease (Mpro) is an attractive therapeutic target that acts in the replication and transcription of the SARS-CoV-2 coronavirus. Mpro is rich in residues exposed to protonation/deprotonation changes which could affect its enzymatic function. This work aimed to explore the effec...

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Detalles Bibliográficos
Autores principales:	Barazorda-Ccahuana, Haruna Luz, Nedyalkova, Miroslava, Mas, Francesc, Madurga, Sergio
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8587287/ https://www.ncbi.nlm.nih.gov/pubmed/34771379 http://dx.doi.org/10.3390/polym13213823

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