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Can the AHCL System Be Used in T1D Patients with Borderline TDDI? A Case Report

(1) Background: Intensive insulin therapy using continuous subcutaneous insulin infusion (CSII) with continuous real-time glucose monitoring (rt CGM) is the best option for patients with T1D. The recent introduction of a technology called Advanced Hybrid Closed Loop (AHCL) represents a new era in th...

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Autores principales: Tekielak, Anna, Seget, Sebastian, Rusak, Ewa, Jarosz-Chobot, Przemysława
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8587306/
https://www.ncbi.nlm.nih.gov/pubmed/34770502
http://dx.doi.org/10.3390/s21217195
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author Tekielak, Anna
Seget, Sebastian
Rusak, Ewa
Jarosz-Chobot, Przemysława
author_facet Tekielak, Anna
Seget, Sebastian
Rusak, Ewa
Jarosz-Chobot, Przemysława
author_sort Tekielak, Anna
collection PubMed
description (1) Background: Intensive insulin therapy using continuous subcutaneous insulin infusion (CSII) with continuous real-time glucose monitoring (rt CGM) is the best option for patients with T1D. The recent introduction of a technology called Advanced Hybrid Closed Loop (AHCL) represents a new era in the treatment of type 1 diabetes, the next step towards better care, as well as improving the effectiveness and safety of therapy. The aim is to present the case of a T1D patient with a borderline total daily dose of insulin being treated with the Medtronic AHCL system in automatic mode. (2) Materials and Methods: A 9-year-old boy, from October 2020, with type 1 diabetes in remission was connected to the Minimed™ 780G (AHCL) system in accordance with the manufacturer’s recommendations (daily insulin dose > 8 units, age > 7). Records of the patient’s history were collected from visits to The Department of Children’s Diabetology, as well as from the Medtronic CareLink™ software and the DPV SWEET program from October 2020 to April 2021. (3) Results: The patient’s total daily insulin requirement decreased in the first 6 weeks after the AHCL was connected, which may reflect the remission phase (tight glycemic control with a healthy lifestyle). The lowest daily insulin requirement of 5.7 units was also recorded. In a three-month follow-up of the patient treated with AHCL, it was found that for almost 38% of the days the insulin dose was less than 8 IU. (4) Conclusions: The AHCL system allows safe and effective insulin therapy in automatic mode, as well as in patients with a lower daily insulin requirement. The AHCL system should be considered a good therapeutic option for patients from the onset of T1D, as well in the remission phase.
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spelling pubmed-85873062021-11-13 Can the AHCL System Be Used in T1D Patients with Borderline TDDI? A Case Report Tekielak, Anna Seget, Sebastian Rusak, Ewa Jarosz-Chobot, Przemysława Sensors (Basel) Case Report (1) Background: Intensive insulin therapy using continuous subcutaneous insulin infusion (CSII) with continuous real-time glucose monitoring (rt CGM) is the best option for patients with T1D. The recent introduction of a technology called Advanced Hybrid Closed Loop (AHCL) represents a new era in the treatment of type 1 diabetes, the next step towards better care, as well as improving the effectiveness and safety of therapy. The aim is to present the case of a T1D patient with a borderline total daily dose of insulin being treated with the Medtronic AHCL system in automatic mode. (2) Materials and Methods: A 9-year-old boy, from October 2020, with type 1 diabetes in remission was connected to the Minimed™ 780G (AHCL) system in accordance with the manufacturer’s recommendations (daily insulin dose > 8 units, age > 7). Records of the patient’s history were collected from visits to The Department of Children’s Diabetology, as well as from the Medtronic CareLink™ software and the DPV SWEET program from October 2020 to April 2021. (3) Results: The patient’s total daily insulin requirement decreased in the first 6 weeks after the AHCL was connected, which may reflect the remission phase (tight glycemic control with a healthy lifestyle). The lowest daily insulin requirement of 5.7 units was also recorded. In a three-month follow-up of the patient treated with AHCL, it was found that for almost 38% of the days the insulin dose was less than 8 IU. (4) Conclusions: The AHCL system allows safe and effective insulin therapy in automatic mode, as well as in patients with a lower daily insulin requirement. The AHCL system should be considered a good therapeutic option for patients from the onset of T1D, as well in the remission phase. MDPI 2021-10-29 /pmc/articles/PMC8587306/ /pubmed/34770502 http://dx.doi.org/10.3390/s21217195 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Case Report
Tekielak, Anna
Seget, Sebastian
Rusak, Ewa
Jarosz-Chobot, Przemysława
Can the AHCL System Be Used in T1D Patients with Borderline TDDI? A Case Report
title Can the AHCL System Be Used in T1D Patients with Borderline TDDI? A Case Report
title_full Can the AHCL System Be Used in T1D Patients with Borderline TDDI? A Case Report
title_fullStr Can the AHCL System Be Used in T1D Patients with Borderline TDDI? A Case Report
title_full_unstemmed Can the AHCL System Be Used in T1D Patients with Borderline TDDI? A Case Report
title_short Can the AHCL System Be Used in T1D Patients with Borderline TDDI? A Case Report
title_sort can the ahcl system be used in t1d patients with borderline tddi? a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8587306/
https://www.ncbi.nlm.nih.gov/pubmed/34770502
http://dx.doi.org/10.3390/s21217195
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