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Synthesis and Toxicity Evaluation of New Pyrroles Obtained by the Reaction of Activated Alkynes with 1-Methyl-3-(cyanomethyl)benzimidazolium Bromide

A series of new pyrrole derivatives were designed as chemical analogs of the 1,4-dihydropyridines drugs in order to develop future new calcium channel blockers. The new tri- and tetra-substituted N-arylpyrroles were synthesized by the one-pot reaction of 1-methyl-3-cyanomethyl benzimidazolium bromid...

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Detalles Bibliográficos
Autores principales:	Ivan, Beatrice-Cristina, Dumitrascu, Florea, Anghel, Adriana Iuliana, Ancuceanu, Robert Viorel, Shova, Sergiu, Dumitrescu, Denisa, Draghici, Constantin, Olaru, Octavian Tudorel, Nitulescu, George Mihai, Dinu, Mihaela, Barbuceanu, Stefania-Felicia
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8587665/ https://www.ncbi.nlm.nih.gov/pubmed/34770844 http://dx.doi.org/10.3390/molecules26216435

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