Preliminary Assessment of the Anti-inflammatory Activity of New Structural Honokiol Analogs with a 4′-O-(2-Fluoroethyl) Moiety and the Potential of Their (18)F-Labeled Derivatives for Neuroinflammation Imaging

Neolignans honokiol and 4′-O-methylhonokiol (MH) and their derivatives have pronounced anti-inflammatory activity, as evidenced by numerous pharmacological studies. Literature data suggested that cyclooxygenase type 2 (COX-2) may be a target for these compounds in vitro and in vivo. Recent studies o...

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Detalles Bibliográficos
Autores principales: Vaulina, Daria D., Stosman, Kira I., Sivak, Konstantin V., Aleksandrov, Andrey G., Viktorov, Nikolai B., Kuzmich, Nikolay N., Kiseleva, Mariia M., Kuznetsova, Olga F., Gomzina, Natalia A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8587714/
https://www.ncbi.nlm.nih.gov/pubmed/34771039
http://dx.doi.org/10.3390/molecules26216630

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8587714/
https://www.ncbi.nlm.nih.gov/pubmed/34771039
http://dx.doi.org/10.3390/molecules26216630

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