3-Phenylcoumarins as a Privileged Scaffold in Medicinal Chemistry: The Landmarks of the Past Decade

3-Phenylcoumarins are a family of heterocyclic molecules that are widely used in both organic and medicinal chemistry. In this overview, research on this scaffold, since 2010, is included and discussed, focusing on aspects related to its natural origin, synthetic procedures and pharmacological appli...

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Detalles Bibliográficos
Autores principales: Matos, Maria J., Uriarte, Eugenio, Santana, Lourdes
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8587835/
https://www.ncbi.nlm.nih.gov/pubmed/34771164
http://dx.doi.org/10.3390/molecules26216755
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author Matos, Maria J.
Uriarte, Eugenio
Santana, Lourdes
author_facet Matos, Maria J.
Uriarte, Eugenio
Santana, Lourdes
author_sort Matos, Maria J.
collection PubMed
description 3-Phenylcoumarins are a family of heterocyclic molecules that are widely used in both organic and medicinal chemistry. In this overview, research on this scaffold, since 2010, is included and discussed, focusing on aspects related to its natural origin, synthetic procedures and pharmacological applications. This review paper is based on the most relevant literature related to the role of 3-phenylcoumarins in the design of new drug candidates. The references presented in this review have been collected from multiple electronic databases, including SciFinder, Pubmed and Mendeley.
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spelling pubmed-85878352021-11-13 3-Phenylcoumarins as a Privileged Scaffold in Medicinal Chemistry: The Landmarks of the Past Decade Matos, Maria J. Uriarte, Eugenio Santana, Lourdes Molecules Review 3-Phenylcoumarins are a family of heterocyclic molecules that are widely used in both organic and medicinal chemistry. In this overview, research on this scaffold, since 2010, is included and discussed, focusing on aspects related to its natural origin, synthetic procedures and pharmacological applications. This review paper is based on the most relevant literature related to the role of 3-phenylcoumarins in the design of new drug candidates. The references presented in this review have been collected from multiple electronic databases, including SciFinder, Pubmed and Mendeley. MDPI 2021-11-08 /pmc/articles/PMC8587835/ /pubmed/34771164 http://dx.doi.org/10.3390/molecules26216755 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Matos, Maria J.
Uriarte, Eugenio
Santana, Lourdes
3-Phenylcoumarins as a Privileged Scaffold in Medicinal Chemistry: The Landmarks of the Past Decade
title 3-Phenylcoumarins as a Privileged Scaffold in Medicinal Chemistry: The Landmarks of the Past Decade
title_full 3-Phenylcoumarins as a Privileged Scaffold in Medicinal Chemistry: The Landmarks of the Past Decade
title_fullStr 3-Phenylcoumarins as a Privileged Scaffold in Medicinal Chemistry: The Landmarks of the Past Decade
title_full_unstemmed 3-Phenylcoumarins as a Privileged Scaffold in Medicinal Chemistry: The Landmarks of the Past Decade
title_short 3-Phenylcoumarins as a Privileged Scaffold in Medicinal Chemistry: The Landmarks of the Past Decade
title_sort 3-phenylcoumarins as a privileged scaffold in medicinal chemistry: the landmarks of the past decade
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8587835/
https://www.ncbi.nlm.nih.gov/pubmed/34771164
http://dx.doi.org/10.3390/molecules26216755
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