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Bone Mineral Density Screening System Using CMOS-Sensor X-ray Detector

This research concerns a design and construction of a bone mineral density (BMD) and bone mineral content (BMC) measurement system based on dual energy X-ray absorptiometry (DEXA). An indirect X-ray detector is designed by optical coupling CMOS sensor with image on the intensifying screen. A dedicat...

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Autores principales: Maneerat, Areerat, Visitsattapongse, Sarinporn, Pintavirooj, Chuchart
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8587857/
https://www.ncbi.nlm.nih.gov/pubmed/34770457
http://dx.doi.org/10.3390/s21217148
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author Maneerat, Areerat
Visitsattapongse, Sarinporn
Pintavirooj, Chuchart
author_facet Maneerat, Areerat
Visitsattapongse, Sarinporn
Pintavirooj, Chuchart
author_sort Maneerat, Areerat
collection PubMed
description This research concerns a design and construction of a bone mineral density (BMD) and bone mineral content (BMC) measurement system based on dual energy X-ray absorptiometry (DEXA). An indirect X-ray detector is designed by optical coupling CMOS sensor with image on the intensifying screen. A dedicated microcontroller X-ray apparatus is used as an X-ray source to capture two energy level X-ray of middle phalanges bone of middle finger. The captured image is processed based on modified Beer-Lambert law to compute bone mineral density. Bone mineral content is also computed by determining the area of the phalanges bone using active contour. The designed bone mineral density (BMD) and bone mineral content (BMC) measurement system is low-cost and hence can be distributed at district hospital for screening purposes of Osteoporosis of the elderly. Compared with BMD measured from commercial model, BMD measurement of our system acquires linear relation with R2 equals 0.969. The mean square error between the normalized BMD value and that of the commercial model is 0.0000981.
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spelling pubmed-85878572021-11-13 Bone Mineral Density Screening System Using CMOS-Sensor X-ray Detector Maneerat, Areerat Visitsattapongse, Sarinporn Pintavirooj, Chuchart Sensors (Basel) Article This research concerns a design and construction of a bone mineral density (BMD) and bone mineral content (BMC) measurement system based on dual energy X-ray absorptiometry (DEXA). An indirect X-ray detector is designed by optical coupling CMOS sensor with image on the intensifying screen. A dedicated microcontroller X-ray apparatus is used as an X-ray source to capture two energy level X-ray of middle phalanges bone of middle finger. The captured image is processed based on modified Beer-Lambert law to compute bone mineral density. Bone mineral content is also computed by determining the area of the phalanges bone using active contour. The designed bone mineral density (BMD) and bone mineral content (BMC) measurement system is low-cost and hence can be distributed at district hospital for screening purposes of Osteoporosis of the elderly. Compared with BMD measured from commercial model, BMD measurement of our system acquires linear relation with R2 equals 0.969. The mean square error between the normalized BMD value and that of the commercial model is 0.0000981. MDPI 2021-10-28 /pmc/articles/PMC8587857/ /pubmed/34770457 http://dx.doi.org/10.3390/s21217148 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Maneerat, Areerat
Visitsattapongse, Sarinporn
Pintavirooj, Chuchart
Bone Mineral Density Screening System Using CMOS-Sensor X-ray Detector
title Bone Mineral Density Screening System Using CMOS-Sensor X-ray Detector
title_full Bone Mineral Density Screening System Using CMOS-Sensor X-ray Detector
title_fullStr Bone Mineral Density Screening System Using CMOS-Sensor X-ray Detector
title_full_unstemmed Bone Mineral Density Screening System Using CMOS-Sensor X-ray Detector
title_short Bone Mineral Density Screening System Using CMOS-Sensor X-ray Detector
title_sort bone mineral density screening system using cmos-sensor x-ray detector
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8587857/
https://www.ncbi.nlm.nih.gov/pubmed/34770457
http://dx.doi.org/10.3390/s21217148
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