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Wound Healing with Electrical Stimulation Technologies: A Review
Electrical stimulation (ES) is an attractive field among clinicians in the topic of wound healing, which is common yet complicated and requires multidisciplinary approaches. The conventional dressing and skin graft showed no promise on complete wound closure. These urge the need for the exploration...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8588136/ https://www.ncbi.nlm.nih.gov/pubmed/34771347 http://dx.doi.org/10.3390/polym13213790 |
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author | Cheah, Yt Jun Buyong, Muhamad Ramdzan Mohd Yunus, Mohd Heikal |
author_facet | Cheah, Yt Jun Buyong, Muhamad Ramdzan Mohd Yunus, Mohd Heikal |
author_sort | Cheah, Yt Jun |
collection | PubMed |
description | Electrical stimulation (ES) is an attractive field among clinicians in the topic of wound healing, which is common yet complicated and requires multidisciplinary approaches. The conventional dressing and skin graft showed no promise on complete wound closure. These urge the need for the exploration of electrical stimulation to supplement current wound care management. This review aims to provide an overview of electrical stimulation in wound healing. The mechanism of galvanotaxis related to wound repair will be reviewed at the cellular and molecular levels. Meanwhile, different modalities of externally applied electricity mimicking a physiologic electric field will be discussed and compared in vitro, in vivo, and clinically. With the emerging of tissue engineering and regenerative medicine, the integration of electroconductive biomaterials into modern miniaturised dressing is of interest and has become possible with the advancing understanding of smart biomaterials. |
format | Online Article Text |
id | pubmed-8588136 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-85881362021-11-13 Wound Healing with Electrical Stimulation Technologies: A Review Cheah, Yt Jun Buyong, Muhamad Ramdzan Mohd Yunus, Mohd Heikal Polymers (Basel) Review Electrical stimulation (ES) is an attractive field among clinicians in the topic of wound healing, which is common yet complicated and requires multidisciplinary approaches. The conventional dressing and skin graft showed no promise on complete wound closure. These urge the need for the exploration of electrical stimulation to supplement current wound care management. This review aims to provide an overview of electrical stimulation in wound healing. The mechanism of galvanotaxis related to wound repair will be reviewed at the cellular and molecular levels. Meanwhile, different modalities of externally applied electricity mimicking a physiologic electric field will be discussed and compared in vitro, in vivo, and clinically. With the emerging of tissue engineering and regenerative medicine, the integration of electroconductive biomaterials into modern miniaturised dressing is of interest and has become possible with the advancing understanding of smart biomaterials. MDPI 2021-11-01 /pmc/articles/PMC8588136/ /pubmed/34771347 http://dx.doi.org/10.3390/polym13213790 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Cheah, Yt Jun Buyong, Muhamad Ramdzan Mohd Yunus, Mohd Heikal Wound Healing with Electrical Stimulation Technologies: A Review |
title | Wound Healing with Electrical Stimulation Technologies: A Review |
title_full | Wound Healing with Electrical Stimulation Technologies: A Review |
title_fullStr | Wound Healing with Electrical Stimulation Technologies: A Review |
title_full_unstemmed | Wound Healing with Electrical Stimulation Technologies: A Review |
title_short | Wound Healing with Electrical Stimulation Technologies: A Review |
title_sort | wound healing with electrical stimulation technologies: a review |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8588136/ https://www.ncbi.nlm.nih.gov/pubmed/34771347 http://dx.doi.org/10.3390/polym13213790 |
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