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Wound Healing with Electrical Stimulation Technologies: A Review

Electrical stimulation (ES) is an attractive field among clinicians in the topic of wound healing, which is common yet complicated and requires multidisciplinary approaches. The conventional dressing and skin graft showed no promise on complete wound closure. These urge the need for the exploration...

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Autores principales: Cheah, Yt Jun, Buyong, Muhamad Ramdzan, Mohd Yunus, Mohd Heikal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8588136/
https://www.ncbi.nlm.nih.gov/pubmed/34771347
http://dx.doi.org/10.3390/polym13213790
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author Cheah, Yt Jun
Buyong, Muhamad Ramdzan
Mohd Yunus, Mohd Heikal
author_facet Cheah, Yt Jun
Buyong, Muhamad Ramdzan
Mohd Yunus, Mohd Heikal
author_sort Cheah, Yt Jun
collection PubMed
description Electrical stimulation (ES) is an attractive field among clinicians in the topic of wound healing, which is common yet complicated and requires multidisciplinary approaches. The conventional dressing and skin graft showed no promise on complete wound closure. These urge the need for the exploration of electrical stimulation to supplement current wound care management. This review aims to provide an overview of electrical stimulation in wound healing. The mechanism of galvanotaxis related to wound repair will be reviewed at the cellular and molecular levels. Meanwhile, different modalities of externally applied electricity mimicking a physiologic electric field will be discussed and compared in vitro, in vivo, and clinically. With the emerging of tissue engineering and regenerative medicine, the integration of electroconductive biomaterials into modern miniaturised dressing is of interest and has become possible with the advancing understanding of smart biomaterials.
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spelling pubmed-85881362021-11-13 Wound Healing with Electrical Stimulation Technologies: A Review Cheah, Yt Jun Buyong, Muhamad Ramdzan Mohd Yunus, Mohd Heikal Polymers (Basel) Review Electrical stimulation (ES) is an attractive field among clinicians in the topic of wound healing, which is common yet complicated and requires multidisciplinary approaches. The conventional dressing and skin graft showed no promise on complete wound closure. These urge the need for the exploration of electrical stimulation to supplement current wound care management. This review aims to provide an overview of electrical stimulation in wound healing. The mechanism of galvanotaxis related to wound repair will be reviewed at the cellular and molecular levels. Meanwhile, different modalities of externally applied electricity mimicking a physiologic electric field will be discussed and compared in vitro, in vivo, and clinically. With the emerging of tissue engineering and regenerative medicine, the integration of electroconductive biomaterials into modern miniaturised dressing is of interest and has become possible with the advancing understanding of smart biomaterials. MDPI 2021-11-01 /pmc/articles/PMC8588136/ /pubmed/34771347 http://dx.doi.org/10.3390/polym13213790 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Cheah, Yt Jun
Buyong, Muhamad Ramdzan
Mohd Yunus, Mohd Heikal
Wound Healing with Electrical Stimulation Technologies: A Review
title Wound Healing with Electrical Stimulation Technologies: A Review
title_full Wound Healing with Electrical Stimulation Technologies: A Review
title_fullStr Wound Healing with Electrical Stimulation Technologies: A Review
title_full_unstemmed Wound Healing with Electrical Stimulation Technologies: A Review
title_short Wound Healing with Electrical Stimulation Technologies: A Review
title_sort wound healing with electrical stimulation technologies: a review
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8588136/
https://www.ncbi.nlm.nih.gov/pubmed/34771347
http://dx.doi.org/10.3390/polym13213790
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