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Thymodepressin—Unforeseen Immunosuppressor
The paper summarizes the available information concerning the biological properties and biomedical applications of Thymodepressin. This synthetic peptide drug displays pronounced immunoinhibitory activity across a wide range of conditions in vitro and in vivo. The history of its unforeseen discovery...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8588242/ https://www.ncbi.nlm.nih.gov/pubmed/34770959 http://dx.doi.org/10.3390/molecules26216550 |
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author | Deigin, Vladislav I. Vinogradova, Julia E. Vinogradov, Dmitry L Krasilshchikova, Marina S. Ivanov, Vadim T. |
author_facet | Deigin, Vladislav I. Vinogradova, Julia E. Vinogradov, Dmitry L Krasilshchikova, Marina S. Ivanov, Vadim T. |
author_sort | Deigin, Vladislav I. |
collection | PubMed |
description | The paper summarizes the available information concerning the biological properties and biomedical applications of Thymodepressin. This synthetic peptide drug displays pronounced immunoinhibitory activity across a wide range of conditions in vitro and in vivo. The history of its unforeseen discovery is briefly reviewed, and the current as well as potential expansion areas of medicinal practice are outlined. Additional experimental evidence is obtained, demonstrating several potential advantages of Thymodepressin over another actively used immunosuppressor drug, cyclosporin A. |
format | Online Article Text |
id | pubmed-8588242 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-85882422021-11-13 Thymodepressin—Unforeseen Immunosuppressor Deigin, Vladislav I. Vinogradova, Julia E. Vinogradov, Dmitry L Krasilshchikova, Marina S. Ivanov, Vadim T. Molecules Article The paper summarizes the available information concerning the biological properties and biomedical applications of Thymodepressin. This synthetic peptide drug displays pronounced immunoinhibitory activity across a wide range of conditions in vitro and in vivo. The history of its unforeseen discovery is briefly reviewed, and the current as well as potential expansion areas of medicinal practice are outlined. Additional experimental evidence is obtained, demonstrating several potential advantages of Thymodepressin over another actively used immunosuppressor drug, cyclosporin A. MDPI 2021-10-29 /pmc/articles/PMC8588242/ /pubmed/34770959 http://dx.doi.org/10.3390/molecules26216550 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Deigin, Vladislav I. Vinogradova, Julia E. Vinogradov, Dmitry L Krasilshchikova, Marina S. Ivanov, Vadim T. Thymodepressin—Unforeseen Immunosuppressor |
title | Thymodepressin—Unforeseen Immunosuppressor |
title_full | Thymodepressin—Unforeseen Immunosuppressor |
title_fullStr | Thymodepressin—Unforeseen Immunosuppressor |
title_full_unstemmed | Thymodepressin—Unforeseen Immunosuppressor |
title_short | Thymodepressin—Unforeseen Immunosuppressor |
title_sort | thymodepressin—unforeseen immunosuppressor |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8588242/ https://www.ncbi.nlm.nih.gov/pubmed/34770959 http://dx.doi.org/10.3390/molecules26216550 |
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