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Thymodepressin—Unforeseen Immunosuppressor

The paper summarizes the available information concerning the biological properties and biomedical applications of Thymodepressin. This synthetic peptide drug displays pronounced immunoinhibitory activity across a wide range of conditions in vitro and in vivo. The history of its unforeseen discovery...

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Detalles Bibliográficos
Autores principales: Deigin, Vladislav I., Vinogradova, Julia E., Vinogradov, Dmitry L, Krasilshchikova, Marina S., Ivanov, Vadim T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8588242/
https://www.ncbi.nlm.nih.gov/pubmed/34770959
http://dx.doi.org/10.3390/molecules26216550
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author Deigin, Vladislav I.
Vinogradova, Julia E.
Vinogradov, Dmitry L
Krasilshchikova, Marina S.
Ivanov, Vadim T.
author_facet Deigin, Vladislav I.
Vinogradova, Julia E.
Vinogradov, Dmitry L
Krasilshchikova, Marina S.
Ivanov, Vadim T.
author_sort Deigin, Vladislav I.
collection PubMed
description The paper summarizes the available information concerning the biological properties and biomedical applications of Thymodepressin. This synthetic peptide drug displays pronounced immunoinhibitory activity across a wide range of conditions in vitro and in vivo. The history of its unforeseen discovery is briefly reviewed, and the current as well as potential expansion areas of medicinal practice are outlined. Additional experimental evidence is obtained, demonstrating several potential advantages of Thymodepressin over another actively used immunosuppressor drug, cyclosporin A.
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spelling pubmed-85882422021-11-13 Thymodepressin—Unforeseen Immunosuppressor Deigin, Vladislav I. Vinogradova, Julia E. Vinogradov, Dmitry L Krasilshchikova, Marina S. Ivanov, Vadim T. Molecules Article The paper summarizes the available information concerning the biological properties and biomedical applications of Thymodepressin. This synthetic peptide drug displays pronounced immunoinhibitory activity across a wide range of conditions in vitro and in vivo. The history of its unforeseen discovery is briefly reviewed, and the current as well as potential expansion areas of medicinal practice are outlined. Additional experimental evidence is obtained, demonstrating several potential advantages of Thymodepressin over another actively used immunosuppressor drug, cyclosporin A. MDPI 2021-10-29 /pmc/articles/PMC8588242/ /pubmed/34770959 http://dx.doi.org/10.3390/molecules26216550 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Deigin, Vladislav I.
Vinogradova, Julia E.
Vinogradov, Dmitry L
Krasilshchikova, Marina S.
Ivanov, Vadim T.
Thymodepressin—Unforeseen Immunosuppressor
title Thymodepressin—Unforeseen Immunosuppressor
title_full Thymodepressin—Unforeseen Immunosuppressor
title_fullStr Thymodepressin—Unforeseen Immunosuppressor
title_full_unstemmed Thymodepressin—Unforeseen Immunosuppressor
title_short Thymodepressin—Unforeseen Immunosuppressor
title_sort thymodepressin—unforeseen immunosuppressor
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8588242/
https://www.ncbi.nlm.nih.gov/pubmed/34770959
http://dx.doi.org/10.3390/molecules26216550
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