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3-O-Carbamoyl-5,7,20-O-trimethylsilybins: Synthesis and Preliminary Antiproliferative Evaluation

To search for novel androgen receptor (AR) modulators for the potential treatment of castration-resistant prostate cancer (CRPC), naturally occurring silibinin was sought after as a lead compound because it possesses a moderate potency towards AR-positive prostate cancer cells and its chemical scaff...

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Detalles Bibliográficos
Autores principales: Wu, Sitong, Chen, Guanglin, Zhang, Qiang, Wang, Guangdi, Chen, Qiao-Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8588252/
https://www.ncbi.nlm.nih.gov/pubmed/34770829
http://dx.doi.org/10.3390/molecules26216421