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A Novel Dual Organocatalyst for the Asymmetric Pinder Reaction and a Mechanistic Proposal Consistent with the Isoinversion Effect Thereof

In general, the Pinder reaction concerns the reaction between an enolisable anhydride and an aldehyde proceeding initially through a Knoevenagel reaction followed by the ring closing process generating lactones with at least two chiral centers. These scaffolds are frequently present in natural produ...

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Detalles Bibliográficos
Autores principales: Moschona, Fotini, Vagena, Athena, Vidali, Veroniki P., Rassias, Gerasimos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8588278/
https://www.ncbi.nlm.nih.gov/pubmed/34770807
http://dx.doi.org/10.3390/molecules26216398