Engineered Fully Human Single-Chain Monoclonal Antibodies to PIM2 Kinase

Proviral integration site of Moloney virus-2 (PIM2) is overexpressed in multiple human cancer cells and high level is related to poor prognosis; thus, PIM2 kinase is a rational target of anti-cancer therapeutics. Several chemical inhibitors targeting PIMs/PIM2 or their downstream signaling molecules...

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Detalles Bibliográficos
Autores principales: Kaewchim, Kanasap, Glab-ampai, Kittirat, Mahasongkram, Kodchakorn, Chulanetra, Monrat, Seesuay, Watee, Chaicumpa, Wanpen, Sookrung, Nitat
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8588357/
https://www.ncbi.nlm.nih.gov/pubmed/34770845
http://dx.doi.org/10.3390/molecules26216436

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8588357/
https://www.ncbi.nlm.nih.gov/pubmed/34770845
http://dx.doi.org/10.3390/molecules26216436

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