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Engineered Fully Human Single-Chain Monoclonal Antibodies to PIM2 Kinase
Proviral integration site of Moloney virus-2 (PIM2) is overexpressed in multiple human cancer cells and high level is related to poor prognosis; thus, PIM2 kinase is a rational target of anti-cancer therapeutics. Several chemical inhibitors targeting PIMs/PIM2 or their downstream signaling molecules...
Autores principales: | Kaewchim, Kanasap, Glab-ampai, Kittirat, Mahasongkram, Kodchakorn, Chulanetra, Monrat, Seesuay, Watee, Chaicumpa, Wanpen, Sookrung, Nitat |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8588357/ https://www.ncbi.nlm.nih.gov/pubmed/34770845 http://dx.doi.org/10.3390/molecules26216436 |
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