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Cardiac resynchronization performed by LBBaP‐CRT in patients with cardiac insufficiency and left bundle branch block

OBJECTIVE: To evaluate the efficacy and safety of left bundle branch area pacing (LBBaP) in patients with heart failure and left bundle branch block (LBBB), and to compare the clinical effects with traditional cardiac resynchronization therapy (CRT). METHODS: Thirty‐two patients with dilated cardiom...

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Autores principales: Zu, Linna, Wang, Zefeng, Hang, Fei, Jiang, Yang, Wang, Xinlu, Cheng, Liting, Zhang, Junmeng, Wu, Yongquan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8588377/
https://www.ncbi.nlm.nih.gov/pubmed/34550625
http://dx.doi.org/10.1111/anec.12898
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author Zu, Linna
Wang, Zefeng
Hang, Fei
Jiang, Yang
Wang, Xinlu
Cheng, Liting
Zhang, Junmeng
Wu, Yongquan
author_facet Zu, Linna
Wang, Zefeng
Hang, Fei
Jiang, Yang
Wang, Xinlu
Cheng, Liting
Zhang, Junmeng
Wu, Yongquan
author_sort Zu, Linna
collection PubMed
description OBJECTIVE: To evaluate the efficacy and safety of left bundle branch area pacing (LBBaP) in patients with heart failure and left bundle branch block (LBBB), and to compare the clinical effects with traditional cardiac resynchronization therapy (CRT). METHODS: Thirty‐two patients with dilated cardiomyopathy complicated by cardiac insufficiency and left bundle branch block were divided into CRT group and LBBaP group. Parameters including pacing threshold, R‐wave amplitude, pacing impedance and operation time, and X‐ray exposure time were recorded. The left ventricular ejection fraction (LVEF), left ventricular end‐diastolic diameter (LVEDD), and left ventricular end‐systolic diameter (LVESD) were examined by echocardiography. The changes of QRS complex before and after operation were compared. RESULTS: Compared with CRT group, the LBBaP group spent less time on total operation time and X‐ray exposure time and had stable electrode parameters including pacing threshold, R‐wave amplitude, and lead impedance after 12‐month follow‐up. In addition, LBBaP can achieve narrow QRS complex (117.15 ± 9.91) ms immediately than that in CRT group (130.32 ± 12.41) ms. The change of QRS between LBBaP is (50.30 ± 23.79) ms and CRT group is (33.15 ± 20.22) ms. After 6 months' follow‐up in LBBaP group, EF was higher than that before operation. Followed up for 12 months after operation, EF and LVEDD in LBBaP group were significantly improved compared with those before operation. CONCLUSION: Left bundle branch area pacing is a safe and effective resynchronization method for patients with cardiac insufficiency and asynchronization, which can achieve same clinical effects to CRT.
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spelling pubmed-85883772021-11-18 Cardiac resynchronization performed by LBBaP‐CRT in patients with cardiac insufficiency and left bundle branch block Zu, Linna Wang, Zefeng Hang, Fei Jiang, Yang Wang, Xinlu Cheng, Liting Zhang, Junmeng Wu, Yongquan Ann Noninvasive Electrocardiol Original Articles OBJECTIVE: To evaluate the efficacy and safety of left bundle branch area pacing (LBBaP) in patients with heart failure and left bundle branch block (LBBB), and to compare the clinical effects with traditional cardiac resynchronization therapy (CRT). METHODS: Thirty‐two patients with dilated cardiomyopathy complicated by cardiac insufficiency and left bundle branch block were divided into CRT group and LBBaP group. Parameters including pacing threshold, R‐wave amplitude, pacing impedance and operation time, and X‐ray exposure time were recorded. The left ventricular ejection fraction (LVEF), left ventricular end‐diastolic diameter (LVEDD), and left ventricular end‐systolic diameter (LVESD) were examined by echocardiography. The changes of QRS complex before and after operation were compared. RESULTS: Compared with CRT group, the LBBaP group spent less time on total operation time and X‐ray exposure time and had stable electrode parameters including pacing threshold, R‐wave amplitude, and lead impedance after 12‐month follow‐up. In addition, LBBaP can achieve narrow QRS complex (117.15 ± 9.91) ms immediately than that in CRT group (130.32 ± 12.41) ms. The change of QRS between LBBaP is (50.30 ± 23.79) ms and CRT group is (33.15 ± 20.22) ms. After 6 months' follow‐up in LBBaP group, EF was higher than that before operation. Followed up for 12 months after operation, EF and LVEDD in LBBaP group were significantly improved compared with those before operation. CONCLUSION: Left bundle branch area pacing is a safe and effective resynchronization method for patients with cardiac insufficiency and asynchronization, which can achieve same clinical effects to CRT. John Wiley and Sons Inc. 2021-09-22 /pmc/articles/PMC8588377/ /pubmed/34550625 http://dx.doi.org/10.1111/anec.12898 Text en © 2021 The Authors. Annals of Noninvasive Electrocardiology published by Wiley Periodicals LLC. https://creativecommons.org/licenses/by/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Articles
Zu, Linna
Wang, Zefeng
Hang, Fei
Jiang, Yang
Wang, Xinlu
Cheng, Liting
Zhang, Junmeng
Wu, Yongquan
Cardiac resynchronization performed by LBBaP‐CRT in patients with cardiac insufficiency and left bundle branch block
title Cardiac resynchronization performed by LBBaP‐CRT in patients with cardiac insufficiency and left bundle branch block
title_full Cardiac resynchronization performed by LBBaP‐CRT in patients with cardiac insufficiency and left bundle branch block
title_fullStr Cardiac resynchronization performed by LBBaP‐CRT in patients with cardiac insufficiency and left bundle branch block
title_full_unstemmed Cardiac resynchronization performed by LBBaP‐CRT in patients with cardiac insufficiency and left bundle branch block
title_short Cardiac resynchronization performed by LBBaP‐CRT in patients with cardiac insufficiency and left bundle branch block
title_sort cardiac resynchronization performed by lbbap‐crt in patients with cardiac insufficiency and left bundle branch block
topic Original Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8588377/
https://www.ncbi.nlm.nih.gov/pubmed/34550625
http://dx.doi.org/10.1111/anec.12898
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