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Saikosaponin A, a Triterpene Saponin, Suppresses Angiogenesis and Tumor Growth by Blocking VEGFR2-Mediated Signaling Pathway

Saikosaponin A (SSA), a main triterpenoid saponin component from Radix Bupleurum, has been revealed to have a variety of pharmacological activities. However, whether SSA can inhibit angiogenesis, a key step in solid tumor progression, remains unknown. In this study, we demonstrated that SSA could po...

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Detalles Bibliográficos
Autores principales:	Zhang, Pan, Lai, Xing, Zhu, Mao-Hua, Long, Mei, Liu, Xue-Liang, Wang, Zi-Xiang, Zhang, Yifan, Guo, Run-Jie, Dong, Jing, Lu, Qin, Sun, Peng, Fang, Chao, Zhao, Mei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8588445/ https://www.ncbi.nlm.nih.gov/pubmed/34776948 http://dx.doi.org/10.3389/fphar.2021.713200

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