Permeability of Ibuprofen in the Form of Free Acid and Salts of L-Valine Alkyl Esters from a Hydrogel Formulation through Strat-M™ Membrane and Human Skin

This paper aimed to evaluate the effect of vehicle and chemical modifications of the structure of active compounds on the skin permeation and accumulation of ibuprofen [IBU]. In vitro permeation experiments were performed using human abdominal skin and Strat-M™ membrane. The HPLC method was used for...

Descripción completa

Detalles Bibliográficos
Autores principales: Klebeko, Joanna, Ossowicz-Rupniewska, Paula, Nowak, Anna, Janus, Ewa, Duchnik, Wiktoria, Adamiak-Giera, Urszula, Kucharski, Łukasz, Prowans, Piotr, Petriczko, Jan, Czapla, Norbert, Bargiel, Piotr, Markowska, Marta, Klimowicz, Adam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8588543/
https://www.ncbi.nlm.nih.gov/pubmed/34772205
http://dx.doi.org/10.3390/ma14216678

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8588543/
https://www.ncbi.nlm.nih.gov/pubmed/34772205
http://dx.doi.org/10.3390/ma14216678

Ejemplares similares