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Permeability of Ibuprofen in the Form of Free Acid and Salts of L-Valine Alkyl Esters from a Hydrogel Formulation through Strat-M™ Membrane and Human Skin

This paper aimed to evaluate the effect of vehicle and chemical modifications of the structure of active compounds on the skin permeation and accumulation of ibuprofen [IBU]. In vitro permeation experiments were performed using human abdominal skin and Strat-M™ membrane. The HPLC method was used for...

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Detalles Bibliográficos
Autores principales:	Klebeko, Joanna, Ossowicz-Rupniewska, Paula, Nowak, Anna, Janus, Ewa, Duchnik, Wiktoria, Adamiak-Giera, Urszula, Kucharski, Łukasz, Prowans, Piotr, Petriczko, Jan, Czapla, Norbert, Bargiel, Piotr, Markowska, Marta, Klimowicz, Adam
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8588543/ https://www.ncbi.nlm.nih.gov/pubmed/34772205 http://dx.doi.org/10.3390/ma14216678

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