Cargando…

Antilymphoma Effect of Incomptine A: In Vivo, In Silico, and Toxicological Studies

Incomptine A (IA) is a sesquiterpene lactone isolated from Decachaeta incompta that induces apoptosis, reactive oxygen species production, and a differential protein expression on the U-937 (diffuse histiocytic lymphoma) cell line. In this work, the antitumor potential of IA was investigated on Balb...

Descripción completa

Detalles Bibliográficos
Autores principales:	Calzada, Fernando, Bautista, Elihú, Hidalgo-Figueroa, Sergio, García-Hernández, Normand, Barbosa, Elizabeth, Velázquez, Claudia, Ordoñez-Razo, Rosa María, Arietta-García, Angel Giovanni
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8588555/ https://www.ncbi.nlm.nih.gov/pubmed/34771055 http://dx.doi.org/10.3390/molecules26216646

Ejemplares similares

Advances in the Properties of Incomptine A: Cytotoxic Activity and Downregulation of Hexokinase II in Breast Cancer Cell Lines
por: Arietta-García, Angel Giovanni, et al.
Publicado: (2023)

Expanding the Study of the Cytotoxicity of Incomptines A and B against Leukemia Cells
por: Calzada, Fernando, et al.
Publicado: (2022)

Incomptine A Induces Apoptosis, ROS Production and a Differential Protein Expression on Non-Hodgkin’s Lymphoma Cells †
por: Pina-Jiménez, Emmanuel, et al.
Publicado: (2021)

Understanding the Anti-Diarrhoeal Properties of Incomptines A and B: Antibacterial Activity against Vibrio cholerae and Its Enterotoxin Inhibition
por: Calzada, Fernando, et al.
Publicado: (2022)

Understanding the Antilymphoma Activity of Annona macroprophyllata Donn and Its Acyclic Terpenoids: In Vivo, In Vitro, and In Silico Studies
por: Ramírez-Santos, Jesica, et al.
Publicado: (2022)

Antitumor Potential of Annona muricata Linn. An Edible and Medicinal Plant in Mexico: In Vitro, In Vivo, and Toxicological Studies
por: Merlín-Lucas, Verenice, et al.
Publicado: (2021)

THE ANTICOAGULANT AND ANTILYMPHOMA PROPERTIES OF ARSENIC AZOPROTEINS : I. ANTICOAGULANT EFFECTS OF ARSENIC AZOPROTEINS IN VIVO AND IN VITRO: COMPARISON OF ARSENICALS AS ANTICOAGULANTS AND AS ANTILYMPHOMA AGENTS: MOLECULAR STRUCTURE IN RELATION TO ANTICOAGULANT AND ANTILYMPHOMA PROPERTIES
por: Broome, J. D., et al.
Publicado: (1964)

Linearolactone Induces Necrotic-like Death in Giardia intestinalis Trophozoites: Prediction of a Likely Target
por: Argüello-García, Raúl, et al.
Publicado: (2022)

Toxicological Screening of Four Bioactive Citroflavonoids: In Vitro, In Vivo, and In Silico Approaches
por: Ortiz-Andrade, Rolffy, et al.
Publicado: (2020)

Antiprotozoal Activities of Tiliroside and other Compounds from Sphaeralcea angustifolia (Cav.) G. Don
por: Calzada, Fernando, et al.
Publicado: (2017)

Antihyperglycemic Activity of the Leaves from Annona cherimola Miller and Rutin on Alloxan-induced Diabetic Rats
por: Calzada, Fernando, et al.
Publicado: (2017)

EVIDENCE THAT THE L-ASPARAGINASE OF GUINEA PIG SERUM IS RESPONSIBLE FOR ITS ANTILYMPHOMA EFFECTS : I. PROPERTIES OF THE L-ASPARAGINASE OF GUINEA PIG SERUM IN RELATION TO THOSE OF THE ANTILYMPHOMA SUBSTANCE
por: Broome, J. D.
Publicado: (1963)

Blocking cholesterol efflux mechanism is a potential target for antilymphoma therapy
por: Yano, Hiromu, et al.
Publicado: (2022)

Inhibition of casein kinase 1δ disrupts translation initiation and exerts potent antilymphoma activity
por: Pal, Ipsita, et al.
Publicado: (2022)

Enhanced systemic antilymphoma immune response by photothermal therapy with CpG deoxynucleotide–coated nanoparticles
por: Lin, Adam Yuh, et al.
Publicado: (2022)

Blockade of CCR1 induces a phenotypic shift in macrophages and triggers a favorable antilymphoma activity
por: Le, Kang, et al.
Publicado: (2023)

Annona cherimola Miller and Its Flavonoids, an Important Source of Products for the Treatment of Diabetes Mellitus: In Vivo and In Silico Evaluations
por: Calzada, Fernando, et al.
Publicado: (2023)

In Silico Toxicology – Non-Testing Methods
por: Raunio, Hannu
Publicado: (2011)

In Vivo and In Silico Study of the Antinociceptive and Toxicological Effect of the Extracts of Petiveria alliacea L. Leaves
por: Cruz-Salomón, Kelly del Carmen, et al.
Publicado: (2022)

Potentiating antilymphoma efficacy of chemotherapy using a liposome for integration of CD20 targeting, ultra-violet irradiation polymerizing, and controlled drug delivery
por: Wu, Cong, et al.
Publicado: (2014)

Toxicological Assessment of Inhaled Nanoparticles: Role of in Vivo, ex Vivo, in Vitro, and in Silico Studies
por: Fröhlich, Eleonore, et al.
Publicado: (2014)

Evaluation of the toxicological effects of atrazine-metolachlor in male rats: in vivo and in silico studies
por: Olayinka, Ebenezer Tunde, et al.
Publicado: (2022)

Ultrastructural and proapoptotic-like effects of kaempferol in Giardia duodenalis trophozoites and bioinformatics prediction of its potential protein target
por: Argüello-García, Raúl, et al.
Publicado: (2020)

Antidiabetic and Toxicological Effects of the Tea Infusion of Summer Collection from Annona cherimola Miller Leaves
por: Martínez-Solís, Jesús, et al.
Publicado: (2022)

In silico toxicology: computational methods for the prediction of chemical toxicity
por: Raies, Arwa B., et al.
Publicado: (2016)

In silico evaluation of apoptogenic potential and toxicological profile of triterpenoids
por: Desai, Tanvi Himanshu, et al.
Publicado: (2019)

Antiprotozoal, Antibacterial and Antidiarrheal Properties from the Flowers of Chiranthodendron pentadactylon and Isolated Flavonoids
por: Calzada, Fernando, et al.
Publicado: (2017)

In silico toxicology models and databases as FDA Critical Path Initiative toolkits
por: Valerio, Luis G
Publicado: (2011)

In Silico Toxicology Data Resources to Support Read-Across and (Q)SAR
por: Pawar, Gopal, et al.
Publicado: (2019)

Discovery of Octahydroisoindolone as a Scaffold for the Selective Inhibition of Chitinase B1 from Aspergillus fumigatus: In Silico Drug Design Studies
por: Marbán-González, Alberto, et al.
Publicado: (2021)

Application of toxicology in silico methods for prediction of acute toxicity (LD(50)) for Novichoks
por: Noga, Maciej, et al.
Publicado: (2023)

Organoids for toxicology and genetic toxicology: applications with drugs and prospects for environmental carcinogenesis
por: Caipa Garcia, Angela L, et al.
Publicado: (2021)

Mycotoxins: Toxicology, Identification and Control
por: Juan García, Cristina
Publicado: (2021)

Toxicology of Metals and Metalloids
por: Júnior, Fernando Barbosa, et al.
Publicado: (2014)

EVIDENCE THAT THE L-ASPARAGINASE OF GUINEA PIG SERUM IS RESPONSIBLE FOR ITS ANTILYMPHOMA EFFECTS : II. LYMPHOMA 6C3HED CELLS CULTURED IN A MEDIUM DEVOID OF L-ASPARAGINE LOSE THEIR SUSCEPTIBILITY TO THE EFFECTS OF GUINEA PIG SERUM IN VIVO
por: Broome, J. D.
Publicado: (1963)

Forced Degradation Studies of Ivabradine and In Silico Toxicology Predictions for Its New Designated Impurities
por: Pikul, Piotr, et al.
Publicado: (2016)

In Vitro and In Silico Toxicological Properties of Natural Antioxidant Therapeutic Agent Azima tetracantha. LAM
por: Prakash, Palanisamy, et al.
Publicado: (2021)

Review of in silico studies dedicated to the nuclear receptor family: Therapeutic prospects and toxicological concerns
por: Sellami, Asma, et al.
Publicado: (2022)

Towards Whole Health Toxicology: In-Silico Prediction of Diseases Sensitive to Multi-Chemical Exposures
por: Arowolo, Olatunbosun, et al.
Publicado: (2022)

Synthesis, In Vitro, In Vivo and In Silico Antidiabetic Bioassays of 4-Nitro(thio)phenoxyisobutyric Acids Acting as Unexpected PPARγ Modulators: An In Combo Study
por: Colin-Lozano, Blanca, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_99k64kqtmqkh29esgmvhogc2am