Disulfide Bonds Play a Critical Role in the Structure and Function of the Receptor-binding Domain of the SARS-CoV-2 Spike Antigen

The current coronavirus pandemic is exerting a tremendously detrimental impact on global health. The Spike proteins of coronaviruses, responsible for cell receptor binding and viral internalization, possess multiple and frequently conserved disulfide bonds raising the question about their role in th...

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Detalles Bibliográficos
Autores principales: Grishin, Andrey M., Dolgova, Nataliya V., Landreth, Shelby, Fisette, Olivier, Pickering, Ingrid J., George, Graham N., Falzarano, Darryl, Cygler, Miroslaw
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8588607/
https://www.ncbi.nlm.nih.gov/pubmed/34780781
http://dx.doi.org/10.1016/j.jmb.2021.167357

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