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ATRX regulates glial identity and the tumor microenvironment in IDH-mutant glioma

BACKGROUND: Recent single-cell transcriptomic studies report that IDH-mutant gliomas share a common hierarchy of cellular phenotypes, independent of genetic subtype. However, the genetic differences between IDH-mutant glioma subtypes are prognostic, predictive of response to chemotherapy, and correl...

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Detalles Bibliográficos
Autores principales:	Babikir, Husam, Wang, Lin, Shamardani, Karin, Catalan, Francisca, Sudhir, Sweta, Aghi, Manish K., Raleigh, David R., Phillips, Joanna J., Diaz, Aaron A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8588616/ https://www.ncbi.nlm.nih.gov/pubmed/34763709 http://dx.doi.org/10.1186/s13059-021-02535-4

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