Cargando…

3D printed customised external cranial plate in a patient with syndrome of trephined: ‘a case report’

BACKGROUND: Syndrome of the trephined is a well-recognised phenomenon that occurs in patients following a craniectomy. It is associated with several symptoms, including headaches, motor impairments, cognitive disorders and reduced consciousness. Treatment for the syndrome usually involves replacing...

Descripción completa

Detalles Bibliográficos
Autores principales: H., Mee, S., Greasley, G., Whiting, C., Harkin, G., Oliver, D., Marsden, R., Andrews, S., Sireau, RD., Price, F., Anwar, IS., Timofeev, PJ., Hutchinson, PA., White, A., Helmy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8588646/
https://www.ncbi.nlm.nih.gov/pubmed/34767106
http://dx.doi.org/10.1186/s41205-021-00123-7
_version_ 1784598520371609600
author H., Mee
S., Greasley
G., Whiting
C., Harkin
G., Oliver
D., Marsden
R., Andrews
S., Sireau
RD., Price
F., Anwar
IS., Timofeev
PJ., Hutchinson
PA., White
A., Helmy
author_facet H., Mee
S., Greasley
G., Whiting
C., Harkin
G., Oliver
D., Marsden
R., Andrews
S., Sireau
RD., Price
F., Anwar
IS., Timofeev
PJ., Hutchinson
PA., White
A., Helmy
author_sort H., Mee
collection PubMed
description BACKGROUND: Syndrome of the trephined is a well-recognised phenomenon that occurs in patients following a craniectomy. It is associated with several symptoms, including headaches, motor impairments, cognitive disorders and reduced consciousness. Treatment for the syndrome usually involves replacing the skull defect. CASE STUDY: A 71-year-old male underwent a left-sided craniectomy after being diagnosed with biopsy-confirmed invasive squamous cell carcinoma with associated skull erosion. Subsequently, he developed a severe case of syndrome of the trephined (SoT,) resulting in having to lie flat to prevent the motor component of the Glasgow Coma Score (GCS) falling from M5/6 (E3/4 Vt M5/6) to M1 (E3/4 Vt M1) on sitting to 30 degrees. Unfortunately, due to ongoing chest sepsis and physical frailty, he was unable to undergo a cranioplasty. Therefore, to aid in clinical stabilisation, the treating physicians and clinical engineering teams designed and manufactured a prosthesis on-site, allowing rapid patient treatment. The prosthesis led to the patient being able to sit up to 30 degrees without the motor component of the GCS falling from M6 to M1 (E4 VT M6). CONCLUSION: Clinical improvements were demonstrated with definitive neurological improvement after applying the external cranial plate in clinical outcome measures and radiographically. Furthermore, we have shown that rapid prototyping technology provides a flexible solution to synthesise bespoke medical prostheses with the correct expertise and regulatory framework.
format Online
Article
Text
id pubmed-8588646
institution National Center for Biotechnology Information
language English
publishDate 2021
publisher Springer International Publishing
record_format MEDLINE/PubMed
spelling pubmed-85886462021-11-15 3D printed customised external cranial plate in a patient with syndrome of trephined: ‘a case report’ H., Mee S., Greasley G., Whiting C., Harkin G., Oliver D., Marsden R., Andrews S., Sireau RD., Price F., Anwar IS., Timofeev PJ., Hutchinson PA., White A., Helmy 3D Print Med Case Report BACKGROUND: Syndrome of the trephined is a well-recognised phenomenon that occurs in patients following a craniectomy. It is associated with several symptoms, including headaches, motor impairments, cognitive disorders and reduced consciousness. Treatment for the syndrome usually involves replacing the skull defect. CASE STUDY: A 71-year-old male underwent a left-sided craniectomy after being diagnosed with biopsy-confirmed invasive squamous cell carcinoma with associated skull erosion. Subsequently, he developed a severe case of syndrome of the trephined (SoT,) resulting in having to lie flat to prevent the motor component of the Glasgow Coma Score (GCS) falling from M5/6 (E3/4 Vt M5/6) to M1 (E3/4 Vt M1) on sitting to 30 degrees. Unfortunately, due to ongoing chest sepsis and physical frailty, he was unable to undergo a cranioplasty. Therefore, to aid in clinical stabilisation, the treating physicians and clinical engineering teams designed and manufactured a prosthesis on-site, allowing rapid patient treatment. The prosthesis led to the patient being able to sit up to 30 degrees without the motor component of the GCS falling from M6 to M1 (E4 VT M6). CONCLUSION: Clinical improvements were demonstrated with definitive neurological improvement after applying the external cranial plate in clinical outcome measures and radiographically. Furthermore, we have shown that rapid prototyping technology provides a flexible solution to synthesise bespoke medical prostheses with the correct expertise and regulatory framework. Springer International Publishing 2021-11-12 /pmc/articles/PMC8588646/ /pubmed/34767106 http://dx.doi.org/10.1186/s41205-021-00123-7 Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Case Report
H., Mee
S., Greasley
G., Whiting
C., Harkin
G., Oliver
D., Marsden
R., Andrews
S., Sireau
RD., Price
F., Anwar
IS., Timofeev
PJ., Hutchinson
PA., White
A., Helmy
3D printed customised external cranial plate in a patient with syndrome of trephined: ‘a case report’
title 3D printed customised external cranial plate in a patient with syndrome of trephined: ‘a case report’
title_full 3D printed customised external cranial plate in a patient with syndrome of trephined: ‘a case report’
title_fullStr 3D printed customised external cranial plate in a patient with syndrome of trephined: ‘a case report’
title_full_unstemmed 3D printed customised external cranial plate in a patient with syndrome of trephined: ‘a case report’
title_short 3D printed customised external cranial plate in a patient with syndrome of trephined: ‘a case report’
title_sort 3d printed customised external cranial plate in a patient with syndrome of trephined: ‘a case report’
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8588646/
https://www.ncbi.nlm.nih.gov/pubmed/34767106
http://dx.doi.org/10.1186/s41205-021-00123-7
work_keys_str_mv AT hmee 3dprintedcustomisedexternalcranialplateinapatientwithsyndromeoftrephinedacasereport
AT sgreasley 3dprintedcustomisedexternalcranialplateinapatientwithsyndromeoftrephinedacasereport
AT gwhiting 3dprintedcustomisedexternalcranialplateinapatientwithsyndromeoftrephinedacasereport
AT charkin 3dprintedcustomisedexternalcranialplateinapatientwithsyndromeoftrephinedacasereport
AT goliver 3dprintedcustomisedexternalcranialplateinapatientwithsyndromeoftrephinedacasereport
AT dmarsden 3dprintedcustomisedexternalcranialplateinapatientwithsyndromeoftrephinedacasereport
AT randrews 3dprintedcustomisedexternalcranialplateinapatientwithsyndromeoftrephinedacasereport
AT ssireau 3dprintedcustomisedexternalcranialplateinapatientwithsyndromeoftrephinedacasereport
AT rdprice 3dprintedcustomisedexternalcranialplateinapatientwithsyndromeoftrephinedacasereport
AT fanwar 3dprintedcustomisedexternalcranialplateinapatientwithsyndromeoftrephinedacasereport
AT istimofeev 3dprintedcustomisedexternalcranialplateinapatientwithsyndromeoftrephinedacasereport
AT pjhutchinson 3dprintedcustomisedexternalcranialplateinapatientwithsyndromeoftrephinedacasereport
AT pawhite 3dprintedcustomisedexternalcranialplateinapatientwithsyndromeoftrephinedacasereport
AT ahelmy 3dprintedcustomisedexternalcranialplateinapatientwithsyndromeoftrephinedacasereport