Polymorphonuclear myeloid-derived suppressor cells impair the anti-tumor efficacy of GD2.CAR T-cells in patients with neuroblastoma

The outcome of patients affected by high-risk or metastatic neuroblastoma (NB) remains grim, with ≥ 50% of the children experiencing relapse or progression of the disease despite multimodal, intensive treatment. In order to identify new strategies to improve the overall survival and the quality of l...

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Detalles Bibliográficos
Autores principales: Tumino, Nicola, Weber, Gerrit, Besi, Francesca, Del Bufalo, Francesca, Bertaina, Valentina, Paci, Paola, Quatrini, Linda, Antonucci, Laura, Sinibaldi, Matilde, Quintarelli, Concetta, Maggi, Enrico, De Angelis, Biagio, Locatelli, Franco, Moretta, Lorenzo, Vacca, Paola, Caruana, Ignazio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Letter to the Editor
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8588686/
https://www.ncbi.nlm.nih.gov/pubmed/34772439
http://dx.doi.org/10.1186/s13045-021-01193-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8588686/
https://www.ncbi.nlm.nih.gov/pubmed/34772439
http://dx.doi.org/10.1186/s13045-021-01193-0

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