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In vivo human molecular neuroimaging of dopaminergic vulnerability along the Alzheimer’s disease phases

BACKGROUND: Preclinical and pathology evidence suggests an involvement of brain dopamine (DA) circuitry in Alzheimer’s disease (AD). We in vivo investigated if, when, and in which target regions [123I]FP-CIT-SPECT regional binding and molecular connectivity are damaged along the AD course. METHODS:...

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Detalles Bibliográficos
Autores principales: Sala, Arianna, Caminiti, Silvia Paola, Presotto, Luca, Pilotto, Andrea, Liguori, Claudio, Chiaravalloti, Agostino, Garibotto, Valentina, Frisoni, Giovanni Battista, D’Amelio, Marcello, Paghera, Barbara, Schillaci, Orazio, Mercuri, Nicola, Padovani, Alessandro, Perani, Daniela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8588696/
https://www.ncbi.nlm.nih.gov/pubmed/34772450
http://dx.doi.org/10.1186/s13195-021-00925-1