Transmission of toxigenic Corynebacterium ulcerans infection with airway obstruction from cats to a human

BACKGROUND: Infections caused by Corynebacterium ulcerans, a zoonotic pathogen, have been reported worldwide. This microorganism is known to produce the diphtheria toxin and cause diphtheria‐like illness. CASE PRESENTATION: A 63‐year‐old woman with a history of diabetes and hypertension developed co...

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Autores principales: Wake, Koji, Kikuchi, Jin, Uchida, Masatoshi, Nemoto, Masato, Kaji, Yoshiyuki, Yokoyama, Tatsuya, Suzuki, Hiromichi, Fukushima, Atsuhito, Yamamoto, Akihiko, Iwaki, Masaaki, Ono, Kazuyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8588950/
https://www.ncbi.nlm.nih.gov/pubmed/34804555
http://dx.doi.org/10.1002/ams2.705
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author Wake, Koji
Kikuchi, Jin
Uchida, Masatoshi
Nemoto, Masato
Kaji, Yoshiyuki
Yokoyama, Tatsuya
Suzuki, Hiromichi
Fukushima, Atsuhito
Yamamoto, Akihiko
Iwaki, Masaaki
Ono, Kazuyuki
author_facet Wake, Koji
Kikuchi, Jin
Uchida, Masatoshi
Nemoto, Masato
Kaji, Yoshiyuki
Yokoyama, Tatsuya
Suzuki, Hiromichi
Fukushima, Atsuhito
Yamamoto, Akihiko
Iwaki, Masaaki
Ono, Kazuyuki
author_sort Wake, Koji
collection PubMed
description BACKGROUND: Infections caused by Corynebacterium ulcerans, a zoonotic pathogen, have been reported worldwide. This microorganism is known to produce the diphtheria toxin and cause diphtheria‐like illness. CASE PRESENTATION: A 63‐year‐old woman with a history of diabetes and hypertension developed cold and flu‐like symptoms, which gradually progressed into respiratory distress. Therefore, the patient was intubated for dyspnea with pseudomembrane formation. A toxin‐producing strain of C. ulcerans was identified, also detected in the patient’s domestic cats. Multilocus sequence typing confirmed all strains, including the patient’s isolate, as ST337. CONCLUSION: Multilocus sequence typing revealed zoonotic transmission of C. ulcerans from domestic cats to a human.
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spelling pubmed-85889502021-11-19 Transmission of toxigenic Corynebacterium ulcerans infection with airway obstruction from cats to a human Wake, Koji Kikuchi, Jin Uchida, Masatoshi Nemoto, Masato Kaji, Yoshiyuki Yokoyama, Tatsuya Suzuki, Hiromichi Fukushima, Atsuhito Yamamoto, Akihiko Iwaki, Masaaki Ono, Kazuyuki Acute Med Surg Case Report BACKGROUND: Infections caused by Corynebacterium ulcerans, a zoonotic pathogen, have been reported worldwide. This microorganism is known to produce the diphtheria toxin and cause diphtheria‐like illness. CASE PRESENTATION: A 63‐year‐old woman with a history of diabetes and hypertension developed cold and flu‐like symptoms, which gradually progressed into respiratory distress. Therefore, the patient was intubated for dyspnea with pseudomembrane formation. A toxin‐producing strain of C. ulcerans was identified, also detected in the patient’s domestic cats. Multilocus sequence typing confirmed all strains, including the patient’s isolate, as ST337. CONCLUSION: Multilocus sequence typing revealed zoonotic transmission of C. ulcerans from domestic cats to a human. John Wiley and Sons Inc. 2021-11-12 /pmc/articles/PMC8588950/ /pubmed/34804555 http://dx.doi.org/10.1002/ams2.705 Text en © 2021 The Authors. Acute Medicine & Surgery published by John Wiley & Sons Australia, Ltd on behalf of Japanese Association for Acute Medicine. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ (https://creativecommons.org/licenses/by-nc-nd/4.0/) License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.
spellingShingle Case Report
Wake, Koji
Kikuchi, Jin
Uchida, Masatoshi
Nemoto, Masato
Kaji, Yoshiyuki
Yokoyama, Tatsuya
Suzuki, Hiromichi
Fukushima, Atsuhito
Yamamoto, Akihiko
Iwaki, Masaaki
Ono, Kazuyuki
Transmission of toxigenic Corynebacterium ulcerans infection with airway obstruction from cats to a human
title Transmission of toxigenic Corynebacterium ulcerans infection with airway obstruction from cats to a human
title_full Transmission of toxigenic Corynebacterium ulcerans infection with airway obstruction from cats to a human
title_fullStr Transmission of toxigenic Corynebacterium ulcerans infection with airway obstruction from cats to a human
title_full_unstemmed Transmission of toxigenic Corynebacterium ulcerans infection with airway obstruction from cats to a human
title_short Transmission of toxigenic Corynebacterium ulcerans infection with airway obstruction from cats to a human
title_sort transmission of toxigenic corynebacterium ulcerans infection with airway obstruction from cats to a human
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8588950/
https://www.ncbi.nlm.nih.gov/pubmed/34804555
http://dx.doi.org/10.1002/ams2.705
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