Saffron offers hepatoprotection via up-regulation of hepatic farnesoid-X-activated receptors in a rat model of acetaminophen-induced hepatotoxicity

OBJECTIVES: The most important toxicity of acetaminophen is hepatotoxicity. Farnesoid X-activated receptors (FXR) are one of the nuclear receptor superfamily members which have a pivotal role in the bile acid regulation. The objective of the present study was to examine the role of FXR in mediating...

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Detalles Bibliográficos
Autores principales: Jamshidi, Vahid, Hashemi, Seyed Ali, Khalili, Azadeh, Fallah, Parviz, Ahmadian-Attari, Mohammad Mahdi, Beikzadeh, Leila, Mazloom, Roham, Najafizadeh, Parvaneh, Bayat, Gholamreza
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mashhad University of Medical Sciences 2021
Materias:
Original Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8588952/
https://www.ncbi.nlm.nih.gov/pubmed/34804899
http://dx.doi.org/10.22038/AJP.2021.18227

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