Human kidney organoids model the tacrolimus nephrotoxicity and elucidate the role of autophagy

BACKGROUND/AIMS: Tacrolimus has been used as an immunosuppressive agent in organ transplantation. Despite the therapeutic benefits, tacrolimus’s use is limited due to its nephrotoxicity. To reduce tacrolimus nephrotoxicity, effective humanized experimental models may be helpful. Here, we modeled tac...

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Detalles Bibliográficos
Autores principales: Kim, Jin Won, Nam, Sun Ah, Seo, Eunjeong, Lee, Jong Young, Kim, Dohui, Ju, Ji Hyeon, Lim, Sun Woo, Kim, Hong Lim, Kim, Hyung Wook, Yang, Chul Woo, Kim, Jin, Kim, Dong Sung, Kim, Yong Kyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Association of Internal Medicine 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8588988/
https://www.ncbi.nlm.nih.gov/pubmed/32972120
http://dx.doi.org/10.3904/kjim.2020.323

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