Cargando…

Genetic Predisposition to Mosaic Chromosomal Loss Is Associated With Functional Outcome After Ischemic Stroke

BACKGROUND AND OBJECTIVES: To test the hypothesis that a predisposition to acquired genetic alterations is associated with ischemic stroke outcome by investigating the association between a polygenic risk score (PRS) for mosaic loss of chromosome Y (mLOY) and outcome in a large international data se...

Descripción completa

Detalles Bibliográficos
Autores principales:	Johansson, Malin, Pedersen, Annie, Cole, John W., Lagging, Cecilia, Lindgren, Arne, Maguire, Jane M., Rost, Natalia S., Söderholm, Martin, Worrall, Bradford B., Stanne, Tara M., Jern, Christina
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Wolters Kluwer 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8589264/ https://www.ncbi.nlm.nih.gov/pubmed/34786478 http://dx.doi.org/10.1212/NXG.0000000000000634

Ejemplares similares

Mosaic Loss of Chromosome Y Is Associated With Functional Outcome After Ischemic Stroke
por: Dorvall, Malin, et al.
Publicado: (2023)

APOE ε4 is associated with younger age at ischemic stroke onset but not with stroke outcome
por: Lagging, Cecilia, et al.
Publicado: (2019)

Investigation of 91 proteins implicated in neurobiological processes identifies multiple candidate plasma biomarkers of stroke outcome
por: Lagging, Cecilia, et al.
Publicado: (2022)

Proteomic profiling identifies novel inflammation-related plasma proteins associated with ischemic stroke outcome
por: Angerfors, Annelie, et al.
Publicado: (2023)

Genome-wide association meta-analysis of functional outcome after ischemic stroke
por: Söderholm, Martin, et al.
Publicado: (2019)

Low admission protein C levels are a risk factor for disease worsening and mortality in hospitalized patients with COVID-19
por: Stanne, Tara M., et al.
Publicado: (2021)

Fibrinogen concentrations predict long‐term cognitive outcome in young ischemic stroke patients
por: Pedersen, Annie, et al.
Publicado: (2018)

Genetic predisposition to mosaic Y chromosome loss in blood
por: Thompson, Deborah J., et al.
Publicado: (2019)

Circulating neurofilament light in ischemic stroke: temporal profile and outcome prediction
por: Pedersen, Annie, et al.
Publicado: (2019)

Longitudinal Study Reveals Long-Term Proinflammatory Proteomic Signature After Ischemic Stroke Across Subtypes
por: Stanne, Tara M., et al.
Publicado: (2022)

Genetic Variation at the BDNF Locus: Evidence for Association with Long-Term Outcome after Ischemic Stroke
por: Stanne, Tara M., et al.
Publicado: (2014)

Fatigue 7 years post‐stroke: Predictors and correlated features
por: Pedersen, Annie, et al.
Publicado: (2022)

A Genome-wide Study of Common and Rare Genetic Variants Associated with Circulating Thrombin Activatable Fibrinolysis Inhibitor
por: Stanne, Tara M., et al.
Publicado: (2018)

Mosaic Loss of Chromosome Y in Blood Is Associated with Alzheimer Disease
por: Dumanski, Jan P., et al.
Publicado: (2016)

Serum IGFBP-1 Concentration as a Predictor of Outcome after Ischemic Stroke—A Prospective Observational Study
por: Åberg, Daniel, et al.
Publicado: (2023)

Differences in Common Genetic Predisposition to Ischemic Stroke by Age and Sex
por: Traylor, Matthew, et al.
Publicado: (2015)

THE EFFECT OF MATERNAL AGE ON CHROMOSOMAL MOSAICISM: AN ANALYSIS BY CHROMOSOME TYPE AND MOSAIC RESULT
por: Reich, Jenna, et al.
Publicado: (2020)

Preimplantation chromosomal mosaics, chimaeras and confined placental mosaicism
por: West, John D, et al.
Publicado: (2022)

Outcome after acute ischemic stroke is linked to sex-specific lesion patterns
por: Bonkhoff, Anna K., et al.
Publicado: (2021)

Chromosomal mosaicism goes global
por: Iourov, Ivan Y, et al.
Publicado: (2008)

MOSAIC CHROMOSOMAL ALTERATIONS AND LONGEVITY
por: Leshchyk, Anastasia, et al.
Publicado: (2022)

First description of revertant mosaicism in familial platelet disorder with predisposition to acute myelogenous leukemia: correlation with the clinical phenotype
por: Glembotsky, Ana C., et al.
Publicado: (2020)

Variations in apolipoprotein D and sigma non-opioid intracellular receptor 1 genes with relation to risk, severity and outcome of ischemic stroke
por: Lövkvist, Håkan, et al.
Publicado: (2014)

Chromosomal radiosensitivity as a marker of predisposition to common cancers?
por: Baria, K, et al.
Publicado: (2001)

The role of X-chromosome inactivation in female predisposition to autoimmunity
por: Chitnis, Smita, et al.
Publicado: (2000)

Genetic Variants of Coagulation Factor XI Show Association with Ischemic Stroke Up to 70 Years of Age
por: Hanson, Ellen, et al.
Publicado: (2013)

ATRT-21. Contribution of germline mosaic alterations of SMARCB1 in rhabdoid tumor predisposition syndrome
por: Masliah-Planchon, Julien, et al.
Publicado: (2022)

Proinflammatory protein signatures in cryptogenic and large artery atherosclerosis stroke
por: Holmegaard, Lukas, et al.
Publicado: (2020)

Genetic Predisposition to Ischemic Stroke: A Polygenic Risk Score
por: Hachiya, Tsuyoshi, et al.
Publicado: (2017)

Mosaic loss of chromosome Y in peripheral blood is associated with shorter survival and higher risk of cancer
por: Forsberg, Lars A., et al.
Publicado: (2014)

Deep profiling of multiple ischemic lesions in a large, multi-center cohort: Frequency, spatial distribution, and associations to clinical characteristics
por: Bonkhoff, Anna K., et al.
Publicado: (2022)

Chromosomal radiosensitivity in head and neck cancer patients: evidence for genetic predisposition?
por: De Ruyck, K, et al.
Publicado: (2008)

Ontogenetic and Pathogenetic Views on Somatic Chromosomal Mosaicism
por: Iourov, Ivan Y., et al.
Publicado: (2019)

Mosaic loss of the Y chromosome and men's health
por: Fukami, Maki, et al.
Publicado: (2022)

The Incidence of Mosaicism for Individual Chromosome in Human Blastocysts Is Correlated With Chromosome Length
por: Chuang, Tzu-Hsuan, et al.
Publicado: (2021)

Chromosomal mosaicism detected by karyotyping and chromosomal microarray analysis in prenatal diagnosis
por: Zhang, Yi, et al.
Publicado: (2020)

Comparison of DNA Methylation Profiles of Hemostatic Genes between Liver Tissue and Peripheral Blood within Individuals
por: Olsson Lindvall, Martina, et al.
Publicado: (2021)

Excessive White Matter Hyperintensity Increases Susceptibility to Poor Functional Outcomes After Acute Ischemic Stroke
por: Hong, Sungmin, et al.
Publicado: (2021)

Chromosomal radiosensitivity in breast cancer patients with a known or putative genetic predisposition
por: Baeyens, A, et al.
Publicado: (2002)

Chromosomal radiosensitivity in breast cancer patients with a known or putative genetic predisposition
por: Seymour, C B, et al.
Publicado: (2003)

Cannot write session to /tmp/vufind_sessions/sess_q011dfkb5vc0he3as5g64e9ehm